Reference : Interferon Response Factor 3 is essential for house dust mite-induced airway allergy
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology Human health sciences : Immunology & infectious disease
http://hdl.handle.net/2268/61914
Interferon Response Factor 3 is essential for house dust mite-induced airway allergy
English
Marichal, Thomas[Université de Liège - ULg > Laboratory of Cellular and Molecular Physiology, GIGA-Research and Faculty of Veterinary Medicine > > > >]
Bedoret, Denis[Université de Liège - ULG > Laboratory of Cellular and Molecular Physiology, GIGA-Research and Faculty of Veterinary Medicine > > >]
Mesnil, Claire[Université de Liège - ULg > Laboratory of Cellular and Molecular Physiology, GIGA-Research and Faculty of Veterinary Medicine > > >]
Pichavant, Muriel[Université de Lille Nord de France, Institut Pasteur de Lille, France > The Lung Infection and Innate Immunity, Team 8, Center for Infection and Immunity of Lille, INSERM U 1019 – CNRS UMR 8204 > > >]
Goriely, Stanislas[Université Libre de Bruxelles - ULB > The Institute for Medical Immunology > > >]
Trottein, François[Université de Lille Nord de France, Institut Pasteur de Lille, France > The Lung Infection and Innate Immunity, Team 8, Center for Infection and Immunity of Lille, INSERM U 1019 – CNRS UMR 8204 > > >]
Cataldo, Didier[Université de Liège - ULg > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, humaines et path. >]
Goldman, Michel[Université Libre de Bruxelles - ULB > The Institute for Medical Immunology > > >]
Lekeux, Pierre[Université de Liège - ULg > Laboratory of Cellular and Molecular Physiology, GIGA-Research and Faculty of Veterinary Medicine > Physiologie - Doyen de la Faculté de Médecine vétérinaire > > >]
Bureau, Fabrice[Université de Liège - ULg > Département de sciences fonctionnelles > GIGA-R : Biochimie et biologie moléculaire >]
Desmet, Christophe[Université de Liège - ULg > Département de sciences fonctionnelles > Physiologie >]
[en] airway allergy ; IRF3 ; IRF7 ; dendritic cell ; type I interferon
[en] IRF3, mainly known as a central orchestrator of antiviral responses, is required for proallergic functions of dendritic cells in response to aeroallergens. Thus, this study demonstratively identifies a new pathway potentially implicated in the etiology of airway allergy
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS (Mandat d'Impulsion Scientifique), Fonds de la Recherche Scientifique Médicale (FRSM; Belgium), and Belgian Programme on Interuniversity Attraction Poles (IUAP; FEDIMMUNE) initiated by the Belgian State (Belgian Science Policy)