Reference : Vitamin D: current status and perspectives.
Scientific journals : Article
Human health sciences : Endocrinology, metabolism & nutrition
Human health sciences : Laboratory medicine & medical technology
http://hdl.handle.net/2268/6161
Vitamin D: current status and perspectives.
English
Cavalier, Etienne [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >]
Delanaye, Pierre [Centre Hospitalier Universitaire de Liège - CHU > > Néphrologie >]
Chapelle, Jean-Paul [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >]
Souberbielle, Jean-Claude [Hôpital Necker - Enfants Malades > Laboratoire d'Explorations fonctionnelles > > >]
2009
Clinical Chemistry & Laboratory Medicine
Walter de Gruyter
47
2
120-127
Yes (verified by ORBi)
International
1434-6621
Berlin
Germany
[en] Abstract The role of vitamin D in maintaining bone health has been known for decades. Recently, however, the discovery that many tissues expressed the vitamin D receptor and were able to transform the 25-OH vitamin D into its most active metabolite, 1,25-(OH)(2) vitamin D, has led to a very promising future for this "old" molecule. Indeed, observational studies, and more and more interventional studies, are raising the importance of a significant vitamin D supplementation for not-only skeletal benefits. Among them, 25-OH vitamin D has been found to play an important role in prevention of cancers, auto-immune diseases, cardiovascular diseases, diabetes, and infections. Vitamin D deficiency, defined as serum 25-OH vitamin D levels <30 ng/mL, is very common in our population. The cost/benefit ratio and some recently published studies are clearly now in favor of a controlled and efficient vitamin D supplementation in these patients presenting a 25-OH vitamin D level <30 ng/mL. More attention should also be focused on pregnant and lactating women, as well as children and adolescents. Clin Chem Lab Med 2009;47.
http://hdl.handle.net/2268/6161
10.1515/CCLM.2009.036

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