Article (Scientific journals)
Nouveaux alcaloïdes des racines du Strychnos icaja
Kambu, Kabangu; Coune, Claude; Angenot, Luc
1979In Planta Medica, 37, p. 161-164
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Keywords :
Strychnos icaja; indole alkaloids; bisnordihydrotoxiferine; sungucine; Nb-methylstrychninium; icajine; 19,20-epoxynovacine; 19,20-epoxy-15-hydroxynovacine
Abstract :
[en] Strychnos icaja roots are used in Central Africa for the preparation of arrow and ordeal poisons. Amongst the very numerous bases present in these roots, we have isolated and identified six alkaloids. Apart from strychnine, we have obtained three alkaloids previously detected in the leaves:icajine, 19,20-alpha-epoxynovacine and 19,20-alpha-epoxy-15-hydroxynovacine. Moreover we have extracted dimeric alkaloids: symmetrical (bisnordihydrotoxiferine) as well as a new unsymmetrical one (sungucine). Finally it has been shown that the plant contained also various quaternary alkaloids and particularly Nb-methylstrychninium base which has been found for the first time. Phytochemical and pharmacological experiments are still under study.
Disciplines :
Phytobiology (plant sciences, forestry, mycology...)
Pharmacy, pharmacology & toxicology
Author, co-author :
Kambu, Kabangu
Coune, Claude
Angenot, Luc  ;  Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Language :
French
Title :
Nouveaux alcaloïdes des racines du Strychnos icaja
Alternative titles :
[en] New alkaloids from the roots of Strychnos icaja
Publication date :
1979
Journal title :
Planta Medica
ISSN :
0032-0943
eISSN :
1439-0221
Publisher :
Georg Thieme Verlag Stuttgart, New York, United States - New York
Volume :
37
Pages :
161-164
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 06 May 2010

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