Altshuler, D., Daly, M. J. & Lander, E. S. (2008) Genetic mapping in human disease. Science 322, 881-888.
Bellman, R. E. (1961) Adaptive control processes: A guided tour. Princeton Princeton University Press.
Calle, M. L., Urrea, V., Vellalta, G., Malats, N. & Van Steen, K. (2008a) Improving strategies for detecting genetic patterns of disease susceptibility in association studies. Stat Med 27, 6532-6546.
Calle, M. L., Urrea, V., Vellalta, G., Malats, N. & Van Steen, K. (2008b) Model-Based Multifactor Dimensionality Reduction for detecting interactions in high-dimensional genomic data. Technical Report No. 24, Department of Systems Biology, Universitat de Vic, .
Cattaert, T., Urrea, V., Naj, A. C., De Lobel, L., De Wit, V., Fu, M., Mahachie John, J. M., Shen, H., Calle, M. L., Ritchie, M. D., Edwards, T. L. & Van Steen, K. (2010) FAM-MDR: A flexible family-base multifactor dimensionality reduction technique to detect epistasis using related individuals. PLoS ONE 5, e10304.
Chung, Y., Lee, S. Y., Elston, R. C. & Park, T. (2007) Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions. Bioinformatics 23, 71-76.
Cordell, H. J. (2002) Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans. Hum Mol Genet 11, 2463-2468.
Cordell, H. J. (2009) Detecting gene-gene interactions that underlie human diseases. Nat Rev Genet 10, 392-404.
Devlin, B. & Roeder, K. (1999) Genomic control for association studies. Biometrics 55, 997-1004.
Dixon, M. S., Golstein, C., Thomas, C. M., Van Der Biezen, E. A. & Jones, J. D. (2000) Genetic complexity of pathogen perception by plants: the example of Rcr3, a tomato gene required specifically by Cf-2. Proc Natl Acad Sci U S A 97, 8807-8814.
Elbers, C. C., Van Eijk, K. R., Franke, L., Mulder, F., Van Der Schouw, Y. T., Wijmenga, C. & Onland-Moret, N. C. (2009) Using genome-wide pathway analysis to unravel the etiology of complex diseases. Genet Epidemiol 33, 419-431.
Greene, C. S., Penrod, N. M., Williams, S. M. & Moore, J. H. (2009) Failure to replicate a genetic association may provide important clues about genetic architecture. PLoS ONE 4, e5639.
Hahn, L. W., Ritchie, M. D. & Moore, J. H. (2003) Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions. Bioinformatics 19, 376-382.
Hardy, J. & Singleton, A. (2009) Genomewide association studies and human disease. N Engl J Med 360, 1759-1768.
Liang, Y. & Kelemen, A. (2008) Statistical advances and challenges for analyzing correlated high dimensional SNP data in genomic study for complex diseases. Statistics Surveys 2, 43-60.
Lou, X. Y., Chen, G. B., Yan, L., Ma, J. Z., Zhu, J., Elston, R. C. & Li, M. D. (2007) A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence. Am J Hum Genet 80, 1125-1137.
Ma, D. Q., Rabionet, R., Konidari, I., Jaworski, J., Cukier, H. N., Wright, H. H., Abramson, R. K., Gilbert, J. R., Cuccaro, M. L., Pericak-Vance, M. A. & Martin, E. R. (2010) Association and Gene-Gene Interaction of SLC6A4 and ITGB3 in Autism. Am J Med Genet B Neuropsychiatr Genet 153B, 477-483.
Mahachie John, J. M., Baurecht, H., Rodríguez, E., Naumann, A., Wagenpfeil, S., Klopp, N., Mempel, M., Novak, N., Bieber, T., Wichmann, H.-E., Ring, J., Illig, T., Cattaert, T., Van Steen, K. & Weidinger, S. (2010) Analysis of the high affinity IgE receptor genes reveals epistatic effects of FCER1A variants on eczema risk. Allergy 65, 875-882.
Manolio, T. A., Brooks, L. D. & Collins, F. S. (2008) A HapMap harvest of insights into the genetics of common disease. J Clin Invest 118, 1590-605.
Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J., Mccarthy, M. I., Ramos, E. M., Cardon, L. R., Chakravarti, A., Cho, J. H., Guttmacher, A. E., Kong, A., Kruglyak, L., Mardis, E., Rotimi, C. N., Slatkin, M., Valle, D., Whittemore, A. S., Boehnke, M., Clark, A. G., Eichler, E. E., Gibson, G., Haines, J. L., Mackay, T. F., Mccarroll, S. A. & Visscher, P. M. (2009) Finding the missing heritability of complex diseases. Nature 461, 747-753.
Marnellos, G. (2003) High-throughput SNP analysis for genetic association studies. Curr Opin Drug Discov Devel 6, 317-321.
McKinney, B. A., Reif, D. M., Ritchie, M. D. & Moore, J. H. (2006) Machine learning for detecting gene-gene interactions: A review. Appl Bioinformatics 5, 77-88.
Moore, J. H. (2003) The ubiquitous nature of epistasis in determining susceptibility to common human diseases. Hum Hered 56, 73-82.
Moore, J. H., Gilbert, J. C., Tsai, C. T., Chiang, F. T., Holden, T., Barney, N. & White, B. C. (2006) A flexible computational framework for detecting, characterizing, and interpreting statistical patterns of epistasis in genetic studies of human disease susceptibility. J Theor Biol 241, 252-261.
Moore, J. H. & White, B. C. (2007) Tuning Relief for Genome-Wide Genetic Analysis. LECT NOTES COMPUT SC 4447, 166-175.
Motsinger, A. A., Ritchie, M. D. & Reif, D. M. (2007) Novel methods for detecting epistasis in pharmacogenomics studies. Pharmacogenomics 8, 1229-1241.
Musani, S. K., Shriner, D., Liu, N., Feng, R., Coffey, C. S., Yi, N., Tiwari, H. K. & Allison, D. B. (2007) Detection of gene x gene interactions in genome-wide association studies of human population data. Hum Hered 63, 67-84.
Onkamo, P. & Toivonen, H. (2006) A survey of data mining methods for linkage disequilibrium mapping. Hum Genomics 2, 336-40.
Pae, C. U., Drago, A., Forlani, M., Patkar, A. A. & Serretti, A. (2010) Investigation of an Epistastic Effect Between a Set of TAAR6 and HSP-70 Genes Variations and Major Mood Disorders. Am J Med Genet B Neuropsychiatr Genet 153B, 680-683.
Park, M. Y. & Hastie, T. (2008) Penalized logistic regression for detecting gene interactions. Biostatistics 9, 30-50.
Ritchie, M. D., Edwards, T. L., Fanelli, T. J. & Motsinger, A. A. (2007) Genetic heterogeneity is not as threatening as you might think. Genet Epidemiol 31, 797-800.
Ritchie, M. D., Hahn, L. W. & Moore, J. H. (2003) Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity. Genet Epidemiol 24, 150-157.
Ritchie, M. D., Hahn, L. W., Roodi, N., Bailey, L. R., Dupont, W. D., Parl, F. F. & Moore, J. H. (2001) Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. Am J Hum Genet 69, 138-147.
Ruczinski, I., Kooperberg, C. & Leblanc, M. L. (2004) Exploring interactions in high-dimensional genomic data: An overview of Logic Regression, with applications. Journal of Multivariate Analysis 90, 178-195.
Seng, K. C. & Seng, C. K. (2008) The success of the genome-wide association approach: A brief story of a long struggle. Eur J Hum Genet 16, 554-564.
Sonoda, T., Suzuki, H., Mori, M., Tsukamoto, T., Yokomizo, A., Naito, S., Fujimoto, K., Hirao, Y., Miyanaga, N. & Akaza, H. (2010) Polymorphisms in estrogen related genes may modify the protective effect of isoflavones against prostate cancer risk in Japanese men. Eur J Cancer Prev 19, 131-137.
Van Steen, K. & Molenberghs, G. (2010) Multicollinearity. In: Encyclopedia of Biopharmaceutical Statistics (ed. S.-C. Chow ), pp. 836-843. London Informa Healthcare.
VanCleave, T. T., Moore, J. H., Benford, M. L., Brock, G. N., Kalbfleisch, T., Baumgartner, R. N., Lillard, J. W., Kittles, R. A. & Kidd, L. C.R. (2010) Interaction Among Variant Vascular Endothelial Growth Factor (VEGF) and Its Receptor in Relation to Prostate Cancer Risk. Prostate 70, 341-352.
Westfall, P. H. & Young, S. S. (1993) Resampling-Based Multiple Testing: Examples and Methods for P-Value Adjustment. New York Wiley.
