Event-related potentials to emotional and neutral stimuli in alcoholism.

Adult; Alcoholism/physiopathology; Case-Control Studies; Diagnostic and Statistical Manual of Mental Disorders; Electroencephalography/instrumentation/methods; Emotions/physiology; Event-Related Potentials, P300/physiology; Female; Humans; Male; Middle Aged; Photic Stimulation; Psychometrics; Reaction Time

Abstract :

[en] Several studies have demonstrated that the emotional value of stimuli affects P300 amplitude. In the present study, the influence of alcohol-related stimuli in alcoholic patients was investigated. Subjects were 10 alcoholic inpatients (3 female) and 10 age- and sex-matched controls. Eight alcohol-related and 8 neutral words served as stimuli in a visual oddball paradigm. Acohol-related words were targets (48 stimuli, 33%) and neutral words were standard stimuli (96 stimuli, 66%). Results showed that P300 amplitude for targets did not differ significantly between the two groups. However, P300 latency for targets as well as reaction time were significantly shorter in male alcoholic patients. In contrast, P300 latency was increased in female alcoholic patients but reaction time did not differ. These results suggest that male alcoholics process information linked to alcohol cues more rapidly than neutral cues, probably because a specific semantic network is activated in these patients. The decreased reaction time confirms the impulsive behavior frequently found in male alcoholism, as it has been described in type II alcoholism. Besides, the results imply that information processing was delayed in female alcoholic patients. Therefore this study demonstrates a gender-dependent impact of alcohol-related stimuli on information processing.

Research center :

Centre de Neurosciences Comportementale et Cognitive

Disciplines :

Neurosciences & behavior

Author, co-author :

Hansenne, Michel ; Université de Liège - ULiège > Département des sciences cognitives > Psycho. de la personnalité et des différences individuelles

Olin, Cecile

Pinto, Emmanuel ; Centre Hospitalier Universitaire de Liège - CHU > Psychiatrie et psychologie médicale

Pitchot, William ; Centre Hospitalier Universitaire de Liège - CHU > Psychiatrie et psychologie médicale

Ansseau, Marc ; Centre Hospitalier Universitaire de Liège - CHU > Psychiatrie et psychologie médicale

Language :

English

Title :

Event-related potentials to emotional and neutral stimuli in alcoholism.

Publication date :

2003

Journal title :

Neuropsychobiology

ISSN :

0302-282X

eISSN :

1423-0224

Publisher :

Karger, Basel, Switzerland

Volume :

Issue :

Pages :

77-81

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 10 February 2009

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