Article (Scientific journals)
Extensive inflammatory pseudotumor of the pituitary.
Hansen, Isabelle; Petrossians, Patrick; Thiry, Albert et al.
2001In Journal of Clinical Endocrinology and Metabolism, 86 (10), p. 4603-4610
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Keywords :
Adrenal Cortex Hormones/therapeutic use; Adult; Female; Granuloma, Plasma Cell/diagnosis/drug therapy/pathology; Humans; Immunohistochemistry; Pituitary Diseases/diagnosis/drug therapy/pathology
Abstract :
[en] A 40-yr-old female presented with an extensive lesion of the sellar area and the sphenoid sinus, spreading to the optic nerves and associated with pachymeningitis. Histological findings were consistent with an inflammatory pseudotumor, and steroid treatment allowed the disappearance of all the lesions. Inflammatory pseudotumors of the pituitary are very rare. This case appears unique with regard to the extension of the lesions and the dramatic response to medical treatment. The differential diagnosis of inflammatory lesions of the pituitary is difficult. It relies mainly on histological analysis and includes sarcoidosis, Wegener's granulomatosis, histiocytosis (Langerhans, Rosai-Dorfman, and Erdheim-Chester diseases) and lymphocytic hypophysitis.
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
Hansen, Isabelle ;  Université de Liège - ULiège > Neurologie Sart Tilman
Petrossians, Patrick  ;  Centre Hospitalier Universitaire de Liège - CHU > Endocrinologie clinique
Thiry, Albert ;  Université de Liège - ULiège > Anatomie pathologique
Flandroy, P.
Gaillard, R. C.
Kovacs, K.
Claes, Frédérique ;  Université de Liège - ULiège > Neurologie Sart Tilman
Stevenaert, Achille ;  Centre Hospitalier Universitaire de Liège - CHU > Neurochirurgie
Piguet, P.
Beckers, Albert ;  Université de Liège - ULiège > Département des sciences cliniques > Endocrinologie
Language :
English
Title :
Extensive inflammatory pseudotumor of the pituitary.
Publication date :
October 2001
Journal title :
Journal of Clinical Endocrinology and Metabolism
ISSN :
0021-972X
eISSN :
1945-7197
Publisher :
Endocrine Society, Chevy Chase, United States - Maryland
Volume :
86
Issue :
10
Pages :
4603-4610
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 18 April 2010

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