Reference : Immunotherapie du cancer par minigreffe de cellules souches hematopoietiques.
Scientific journals : Article
Human health sciences : Hematology
http://hdl.handle.net/2268/5964
Immunotherapie du cancer par minigreffe de cellules souches hematopoietiques.
French
[en] Nonmyeloablative stem cell transplantation as cancer immunotherapy
Willems, Evelyne mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
Baron, Frédéric mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
Vanstraelen, Gaëtan mailto [> > > >]
Frere, Pascale mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
Fillet, Georges mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
Beguin, Yves mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
2005
Revue Médicale Suisse
1
30
1973-7
Yes (verified by ORBi)
International
1660-9379
Switzerland
[en] Hematologic Neoplasms/therapy ; Hematopoietic Stem Cell Transplantation ; Humans ; Immunotherapy ; Transplantation Conditioning ; Transplantation, Homologous ; Treatment Outcome
[en] Allogeneic hematopoietic stem cell transplantation (HSCT) is used for the treatment of selected haematological malignancies. Its curative potential is based on two different mechanisms, i.e. the conditioning regimen and the graft-versus-host immunologic reactions. However, because of its toxicity, it is restricted to younger and fitter patients. These observations led several groups to set up new (less toxic) transplant protocols. These transplants are called nonmyeloablative HSCT or minitransplants. These are feasible with a relatively low transplant-related mortality even in patients up to 70 years. In addition, strong anti-tumor responses are observed in several haematological malignancies.
http://hdl.handle.net/2268/5964

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