Reference : Efficacy of recombinant human erythropoietin therapy started one month after autologous ...
Scientific journals : Article
Human health sciences : Hematology
http://hdl.handle.net/2268/5963
Efficacy of recombinant human erythropoietin therapy started one month after autologous peripheral blood stem cell transplantation.
English
Vanstraelen, Gaetan mailto [> > > >]
Baron, Frédéric mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
Frere, Pascale mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
Hafraoui, Kaoutar mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
Fillet, Georges mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
Beguin, Yves mailto [Centre Hospitalier Universitaire de Liège - CHU > > Hématologie clinique >]
2005
Haematologica
Ferrata Storti Foundation
90
9
1269-70
Yes (verified by ORBi)
International
0390-6078
1592-8721
Pavia
Italy
[en] Aged ; Erythropoietin, Recombinant/therapeutic use ; Female ; Hematologic Diseases/blood/surgery ; Humans ; Male ; Middle Aged ; Peripheral Blood Stem Cell Transplantation/methods ; Transplantation, Autologous
[en] On day 30 after autologous peripheral blood stem cell transplantation (PBSCT), 20 patients were randomized to receive either erythropoietin at a dose of 500 U/kg/week s.c. (Epo group) or no treatment (control group). After 3 weeks, hemoglobin (p<0.0001) and serum transferrin receptor (p<0.0001) concentrations were higher in the Epo group. Hb response (+2 g/dL) was achieved in 100% vs 28% (p<0.0001) and Hb correction (> or =13 g/dL) in 70% vs 10% (p=0.0238) of the patients, respectively. This is the first randomized study showing an efficacy of erythropoietin therapy on Hb levels after autologous PBSCT.
http://hdl.handle.net/2268/5963

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