ORBi: Plenevaux Alain - [(18)F]P-Mppf: Aa Radiolabeled Antagonist for the Study of 5-Ht(1a) Receptors with Pet

Reference : [(18)F]P-Mppf: Aa Radiolabeled Antagonist for the Study of 5-Ht(1a) Receptors with Pet


	Document type :	Scientific journals : Article
	Discipline(s) :	Physical, chemical, mathematical & earth Sciences : Multidisciplinary, general & others
	To cite this reference:	http://hdl.handle.net/2268/5954

Title :	[(18)F]P-Mppf: Aa Radiolabeled Antagonist for the Study of 5-Ht(1a) Receptors with Pet
Language :	English
Author, co-author :	Plenevaux, Alain [Université de Liège - ULg > > Centre de recherches du cyclotron >]
	Lemaire, Christian [Université de Liège - ULg > > Centre de recherches du cyclotron >]
	Aerts, Joël [Université de Liège - ULg > > Centre de recherches du cyclotron >]
	Lacan, Goran [UCLA School of Medicine > Molecular and Medical Pharmacology >]
	Rubins, D. [UCLA School of Medicine > Molecular and Medical Pharmacology >]
	Melega, William P. [UCLA School of Medicine > Molecular and Medical Pharmacology >]
	Brihaye, Claude [Université de Liège - ULg > > Centre de recherches du cyclotron >]
	Degueldre, Christian [Université de Liège - ULg > > Centre de recherches du cyclotron >]
	Fuchs, Sonia [Université de Liège - ULg > > Centre de recherches du cyclotron >]
	Salmon, Eric [Université de Liège - ULg > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn. >]
	Maquet, Pierre [Université de Liège - ULg > > Centre de recherches du cyclotron]
	Laureys, Steven [Université de Liège - ULg > > Centre de recherches du cyclotron]
	Damhaut, Philippe [> > > >]
	Weissmann, D. [> > > >]
	Le Bars, Didier [> > > >]
	Pujol, Jean-François [> > > >]
	Luxen, André [Université de Liège - ULg > Département de chimie (sciences) > Chimie organique de synthèse - Centre de recherches du cyclotron >]
Publication date :	Jul-2000
Journal title :	Nuclear Medicine & Biology
Volume :	27
Issue/season :	5
Pages :	467-71
Audience :	International
ISSN :	0969-8051
Keywords :	[en] 5-HT1A ; Receptor ; MPPF
	[fr] Fluorine-18 ; PET ; MicroPET
Abstract :	[en] This paper summarizes the present status of the researches conducted with [(18)F]4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p-fluorobenzamido ]ethyl]-piperazine known as [(18)F]p-MPPF, a new 5-HT(1A) antagonist for the study of the serotonergic neurotransmission with positron emission tomography (PET). This includes chemistry, radiochemistry, animal data (rats, cats, and monkeys) with autoradiography and PET, human data with PET, toxicity, and metabolism.
Research units :	INSERM/CFB
Funders :	Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Permalink :	http://hdl.handle.net/2268/5954

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