ORBi: Remy Benoit - Are Antibodies Responsible for a Decreased Superovulatory Response in Goats Which Have Been Treated Repeatedly with Porcine Follicle-Stimulating Hormone ?

Reference : Are Antibodies Responsible for a Decreased Superovulatory Response in Goats Which Have B...


	Document type :	Scientific journals : Article
	Discipline(s) :	Life sciences : Veterinary medicine & animal health
	To cite this reference:	http://hdl.handle.net/2268/5795

Title :	Are Antibodies Responsible for a Decreased Superovulatory Response in Goats Which Have Been Treated Repeatedly with Porcine Follicle-Stimulating Hormone ?
Language :	English
Author, co-author :	Remy, Benoit [Université de Liège - ULG > Faculté de Médecine vétérinaire > > >]
	Baril, Gérard [Institut Scientifique de Recherche Agronomique - INRA > Physiologie de la reproduction Nouzilly > > >]
	Vallet, J. C. [Institut Scientifique de Recherche Agronomique - INRA > Physiologie de la reproduction Nouzilly > > >]
	Dufour, R. [IFFA Mérieux Lyon France > > > > > >]
	Chouvet, Claire [IFFA Mérieux Lyon France > > > > > >]
	Saumande, Jean [Institut Scientifique de Recherche Agronomique - INRA > Physiologie de la reproduction Nouzilly > > >]
	Chupin, D. [Institut Scientifique de Recherche Agronomique - INRA > Physiologie de la reproduction Nouzilly > > >]
	Beckers, Jean-François [Université de Liège - ULg > Département de sciences fonctionnelles > Physiologie de la reproduction >]
Publication date :	Sep-1991
Journal title :	Theriogenology
Publisher :	Elsevier
Volume :	36
Issue/season :	3
Pages :	389-99
Audience :	International
ISSN :	0093-691X
City :	New York
Country :	NY
Keywords :	[en] Superovulation ; Gonadotropins ; Antibodies ; Goats ; Refractoriness
Abstract :	[en] Repeated administration of xenogenic gonadotropins in human or animal species may be responsible for antibody production and refractoriness. An experiment was conducted in which goats were treated with porcine FSH (p-FSH) at 6-week intervals for a period of 7 months. A sensitive radioimmunoassay (RIA) was used to detect antibodies to p-FSH in plasma samples taken at short-term intervals during a 7-month period. Antibodies appeared after the first injection, and levels increased following booster injections. A high correlation rate existed between antibody level and superovulatory response. Refractoriness in goats was associated with a high level of antibodies.
Research units :	Laboratoire d'Endocrinologie et de Physiologie de la Reproduction animale
Funders :	I.R.S.I.A.
Target :	Researchers ; Professionals ; Students
Permalink :	http://hdl.handle.net/2268/5795

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