ORBi: Grignard Bruno - Synthesis of biodegradable poly-epsilon-caprolactone microspheres by dispersion ring-opening polymerization in supercritical carbon dioxide

Reference : Synthesis of biodegradable poly-epsilon-caprolactone microspheres by dispersion ring-ope...


	Document type :	Scientific journals : Article
	Discipline(s) :	Physical, chemical, mathematical & earth Sciences : Chemistry Engineering, computing & technology : Materials science & engineering
	To cite this reference:	http://hdl.handle.net/2268/5739

Title :	Synthesis of biodegradable poly-epsilon-caprolactone microspheres by dispersion ring-opening polymerization in supercritical carbon dioxide
Language :	English
Author, co-author :	Grignard, Bruno [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
	Stassin, Fabrice [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
	Calberg, Cédric [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
	Jérôme, Robert [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
	Jérôme, Christine [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
Publication date :	10-Nov-2008
Journal title :	Biomacromolecules
Publisher :	American Chemical Society
Volume :	9
Issue/season :	11
Pages :	3141-3149
Peer reviewed :	Yes (verified by ORBi)
Audience :	International
ISSN :	1525-7797
e-ISSN :	1526-4602
City :	Washington
Country :	DC
Keywords :	[en] green technology ; supercritical carbon dioxide ; ring-opening polymerization (ROP) ; lactone
Abstract :	[en] A series of fluorinated diblock and triblock copolymers of poly(ε-caprolactone) and poly(heptadecafluorodecylacrylate) were prepared by combining ring-opening polymerization of ε-CL and atom transfer radical polymerization of the acrylate. These copolymers with well-controlled molecular weight and composition were characterized by 1H NMR spectroscopy and used as stabilizers for the dispersion ring-opening polymerization of ε-CL in supercritical carbon dioxide. The effect of composition and architecture of the polymeric stabilizers on the stabilization of PCL microspheres was investigated. Finally, purification of PCL was successfully implemented by reactive supercritical fluid extraction of the tin catalyst.
Research units :	Center for Education and Research on Macromolecules (CERM)
Funders :	Politique Scientifique Fédérale (Belgique) = Belgian Federal Science Policy ; The European Community for a fellowship of the “Polymerization and Polymer Modification in Supercritical Fluids: A Novel Way for Cleaner Manufacturing of Plastics (SUPERPOL)” project ; The Région Wallonne for the financial support of the “Technologie et Matériaux Polymèes Innovants Préservants 1′Environnement (TECMAVER)” project
Target :	Researchers
Permalink :	http://hdl.handle.net/2268/5739
DOI :	10.1021/bm800730m
Other URL :	http://pubs.acs.org/doi/pdf/10.1021/bm800730m

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