Reference : Primary Structure of Selected Archaeal Mesophilic and Extremely Thermophilic Outer Su...
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/2268/57072
Primary Structure of Selected Archaeal Mesophilic and Extremely Thermophilic Outer Surface Layer Proteins
English
Claus, Harald [Johannes Gutenberg-Universität - Mainz > > > >]
Akça, Erol [Johannes Gutenberg-Universität - Mainz > > > >]
Debaerdemaeker, Tony [Universität Ulm > > > >]
Evrard, Christine mailto [Université Catholique de Louvain - UCL > Département de Chimie > Laboratoire de Chimie et de Cristallographie > >]
Declercq, Jean-Paul mailto [Université Catholique de Louvain - UCL > Département de Chimie > Laboratoire de Chimie et de Cristallographie > >]
König, Helmut [Johannes Gutenberg-Universität - Mainz > > > >]
2002
Systematic & Applied Microbiology
Elsevier GmbH, Urban & Fischer Verlag
25
3-12
Yes (verified by ORBi)
International
0723-2020
Jena
Germany
[en] Archaea ; cell walls ; S-layer ; (glyco-)proteins ; protein structure
[en] The archaea are recognized as a separate third domain of life together with the bacteria and eucarya. The
archaea include the methanogens, extreme halophiles, thermoplasmas, sulfate reducers and sulfur metabolizing
thermophiles, which thrive in different habitats such as anaerobic niches, salt lakes, and marine
hydrothermals systems and continental solfataras. Many of these habitats represent extreme environments
in respect to temperature, osmotic pressure and pH-values and remind on the conditions of the
early earth. The cell envelope structures were one of the first biochemical characteristics of archaea studied
in detail. The most common archaeal cell envelope is composed of a single crystalline protein or glycoprotein
surface layer (S-layer), which is associated with the outside of the cytoplasmic membrane. The
S-layers are directly exposed to the extreme environment and can not be stabilized by cellular components.
Therefore, from comparative studies of mesophilic and extremely thermophilic S-layer proteins
hints can be obtained about the molecular mechanisms of protein stabilization at high temperatures.
First crystallization experiments of surface layer proteins under microgravity conditions were successful.
Here, we report on the biochemical features of selected mesophilic and extremely archaeal S-layer (glyco-)
proteins.
http://hdl.handle.net/2268/57072
http://www.elsevier.com/wps/find/journaldescription.cws_home/701801/description#description

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