Article (Scientific journals)
Five labdane diterpenoids from the seeds of Aframomum zambesiacum
Kenmogne, Marguerite; Prost, Elise; Harakat, Dominique et al.
2006In Phytochemistry, 67 (5), p. 433-438
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Keywords :
Aframomum zambesiacum; Zingiberaceae; labdane diterpenoids; antiplasmodial activity; Plasmodium falciparum
Abstract :
[en] Five labdane diterpenoids, (3-5), zambesiacolactone A (7) and zambesiacolactone B (8), were isolated from the seeds of Aframomum zambesiacum (Baker) K. Schum., along with five known labdanes and a linear sesquiterpene, nerolidol. Their structures were elucidated by spectroscopic analysis. Their antiplasmodial activity was evaluated in vitro against Plasmodium falciparum. Compound 3 was the most active with an IC50 value of 4.97 mu M. (c) 2005 Elsevier Ltd. All rights reserved.
Disciplines :
Biochemistry, biophysics & molecular biology
Phytobiology (plant sciences, forestry, mycology...)
Author, co-author :
Kenmogne, Marguerite;  University of Dschang (Cameroun) > Faculty of Science > Department of Chemistry
Prost, Elise;  Université de Reims Champagne-Ardenne - URCA
Harakat, Dominique;  Université de Reims Champagne-Ardenne - URCA > Faculté des Sciences > Laboratoire "Réactions Sélectives et Applications’’ > UMR CNRS 6519
Jacquier, Marie-José;  Université de Reims Champagne-Ardenne - URCA
Frederich, Michel  ;  Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Sondengam, Lucas B.;  University of Yaoundé I > Faculty of Science > Department of Organic Chemistry
Zèches, Monique;  Université de Reims Champagne-Ardenne - URCA
Waffo-Téguo, Pierre;  Université de Reims Champagne-Ardenne - URCA
Language :
English
Title :
Five labdane diterpenoids from the seeds of Aframomum zambesiacum
Publication date :
March 2006
Journal title :
Phytochemistry
ISSN :
0031-9422
eISSN :
1873-3700
Publisher :
Pergamon-Elsevier Science Ltd, Oxford, United Kingdom
Volume :
67
Issue :
5
Pages :
433-438
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 05 February 2009

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