ORBi: Ouattara Badiore - LC/MS/NMR analysis of isomeric divanilloylquinic acids from the root bark of Fagara zanthoxyloides Lam

Reference : LC/MS/NMR analysis of isomeric divanilloylquinic acids from the root bark of Fagara zant...


	Document type :	Scientific journals : Article
	Discipline(s) :	Human health sciences : Pharmacy, pharmacology & toxicology Life sciences : Phytobiology (plant sciences, forestry, mycology...) Physical, chemical, mathematical & earth Sciences : Chemistry
	To cite this reference:	http://hdl.handle.net/2268/5619

Title :	LC/MS/NMR analysis of isomeric divanilloylquinic acids from the root bark of Fagara zanthoxyloides Lam
Language :	English
Author, co-author :	Ouattara, Badiore [Institut de Recherche en Sciences de la Santé (IRSS) Ouagadougou > Médecine-Pharmacopée Traditionnelle / Pharmacie > > >]
	Angenot, Luc [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
	Guissou, Pierre [Institut de Recherche en Sciences de la Santé (IRSS) Ouagadougou > Département Médecine-Pharmacopée Traditionnelle / Pharmacie > > >]
	Fondu, Pierre [Université Libre de Bruxelles - ULB > Hopital Universitaire Brugmann > Laboratoire d'Hématologie > >]
	Dubois, Jacques [Université Libre de Bruxelles - ULB > Pharmacie > Chimie Analytique > >]
	Frederich, Michel [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
	Jansen, Olivia [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
	Van Heugen, Jean-Claude [Centre Hospitalier Universitaire de Liège - CHU > > Chimie médicale >]
	Wauters, Jean-Noël [Université de Liège - ULg > Département de pharmacie > Département de pharmacie >]
	Tits, Monique [Université de Liège - ULg > Département de pharmacie > Phytochimie et phytothérapie >]
Publication date :	Apr-2004
Journal title :	Phytochemistry
Publisher :	Pergamon-Elsevier Science Ltd
Volume :	65
Issue/season :	8
Pages :	1145-1151
Audience :	International
ISSN :	0031-9422
City :	Oxford
Keywords :	[en] Fagara zanthoxyloides ; Rutaceae ; divanilloylquinic acids ; burkinabins A-C ; HPLC/MS/NMR ; antisickling activity
Abstract :	[en] Gradient HPLC coupled to DAD/UV, MS/MS and NMR has been applied to the rapid structure determination of three new isomeric divanilloylquinic acids from Fagara zanthoxyloides collected in Burkina Faso: 3,4-O-divanilloylquinic acid, 3,5-O-divanilloylquinic acid and 4,5-O-divanilloylquinic acid. Furthermore these new compounds named burkinabins A-C could play a useful role in sickle cell disease, as the active agents of Fagara zanthoxyloides are said to be unidentified aromatic compounds with carboxylic acid grouping (Adesanya, S.A., Sofowora, A., 1983. Biological standardisation of Zanthoxylum roots for antisickling activity. Planta Med. 48, 27-33). (C) 2004 Elsevier Ltd. All rights reserved.
Target :	Researchers ; Professionals
Permalink :	http://hdl.handle.net/2268/5619
DOI :	10.1016/j.phytochem.2004.02.025

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