Reference : In vitro cytotoxicity of some medicinal plants from Georgian amaryllidaceae
Scientific journals : Article
Physical, chemical, mathematical & earth Sciences : Chemistry
Human health sciences : Pharmacy, pharmacology & toxicology
http://hdl.handle.net/2268/5602
In vitro cytotoxicity of some medicinal plants from Georgian amaryllidaceae
English
Jokhadze, Malkhaz [> Tbilissi State Medical University (Georgia) > > Pharmacy > Pharmacognosy > >]
Eristavi, Lina [> Tbilissi State Medical University (Georgia) > > Pharmacy > Pharmacognosy > >]
Kutchukhidze, Jumber [> Tbilissi State Medical University (Georgia) > > Pharmacy > Pharmacognosy > >]
Chariot, Alain mailto [Université de Liège - ULg > Département de pharmacie > Chimie médicale >]
Angenot, Luc mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Tits, Monique mailto [Université de Liège - ULg > Département de pharmacie > Phytochimie et phytothérapie >]
Jansen, Olivia mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Frederich, Michel mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Jul-2007
Phytotherapy Research
John Wiley & Sons Ltd
21
7
622-624
Yes (verified by ORBi)
International
0951-418X
Chichester
[en] amaryllidaceae ; Galanthus ; Leucojum ; cancer ; cytotoxicity
[en] Using an ethnomedical data approach, some Georgian plants, which are used in Georgian traditional medicine for cancer or non-cancer diseases, were collected and evaluated for cytotoxic activity. The cytotoxic effect of the methanol extracts of species from the genera Galanthus and Leucojum was evaluated in vitro on three human cell lines (Hela, ephitheloid cervix carcinoma; HCT-116, colon carcinoma; HL-60, acute myeloid leukaemia). Cell type cytotoxic specificity was observed for some extracts. Overall, the HCT-116 cells were much more sensitive to most of the extracts than were the other cell lines. Plants that showed pronounced cytotoxic activity will be further evaluated for the possible isolation of active antitumour compounds. Copyright (C) 2007 John Wiley
Researchers ; Professionals
http://hdl.handle.net/2268/5602

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