Reference : Metabolomic analysis of Strychnos nux-vomica, Strychnos icaja and Strychnos ignatii extr...
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
Life sciences : Phytobiology (plant sciences, forestry, mycology...)
http://hdl.handle.net/2268/5589
Metabolomic analysis of Strychnos nux-vomica, Strychnos icaja and Strychnos ignatii extracts by H-1 nuclear magnetic resonance spectrometry and multivariate analysis techniques
English
Frederich, Michel mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Choi, Young Hae [> > > >]
Angenot, Luc mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Harnischfeger, Goetz [> > > >]
Lefeber, Alfons W. M. [> > > >]
Verpoorte, Robert [> > > >]
Jul-2004
Phytochemistry
Pergamon-Elsevier Science Ltd
65
13
1993-2001
Yes (verified by ORBi)
International
0031-9422
Oxford
[en] loganiaceae ; Strychmos nux-vomica ; Strychnos ignatii ; Strychnos icaja ; strychnine ; brucine ; metabolic profiling ; H-1 NMR ; multivariate analysis ; PCA ; alkaloid
[en] H-1 Nuclear magnetic resonance spectrometry and multivariate analysis techniques were applied for the metabolic profiling of three Strychnos species: Strychnos nux-vomica (seeds, stem bark, root bark), Strychnos ignatii (seeds), and Strychnos icaja (leaves, stem bark, root bark, collar bark). The principal component analysis (PCA) of the H-1 NMR spectra showed a clear discrimination between all samples, using the three first components. The key compounds responsible for the discrimination were brucine, loganin, fatty acids.. and Strychnos icaja alkaloids such as icajine and sungucine. The method was then applied to the classification of several "false angostura" samples. These samples were, as expected, identified as S. nux-vomica by PCA, but could not be clearly discriminated as root bark or stem bark samples after further statistical analysis. (C) 2004 Published by Elsevier Ltd.
http://hdl.handle.net/2268/5589

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