Reference : Staging of primary cervical cancers: the role of nuclear medicine
Scientific journals : Letter to the editor
Human health sciences : Oncology
Human health sciences : Hematology
http://hdl.handle.net/2268/5521
Staging of primary cervical cancers: the role of nuclear medicine
English
Belhocine, Tarik [> > > >]
Kridelka, Frédéric mailto [Université de Liège - ULg > Département des sciences cliniques > Gynécologie et obstétrique]
Thille, Alain [Centre Hospitalier Universitaire de Liège - CHU > > Imagerie médicale >]
De Barsy, Caroline [> > > >]
Foidart-Willems, Jacqueline [> > > >]
Hustinx, Roland mailto [Université de Liège - ULg > Département des sciences cliniques > Médecine nucléaire]
Rigo, Pierre mailto [Université de Liège - ULg > Département des sciences de la motricité > Pathologie générale et médecine nucléaire >]
Jun-2003
Critical Reviews in Oncology/Hematology
Elsevier Science Inc
46
3
275-284
Yes (verified by ORBi)
International
1040-8428
New York
[en] cervical cancer ; positron emission tomography ; F-18-fluorodeoxyglucose ; lymphatic mapping ; sentinel lymphadenectomy
[en] In nuclear medicine, [F-18]-fluorodeoxyglucose positron emission tomography ((18)FDG PET) and lymphatic mapping and sentinel lymphadenectomy (LM/SL) may significantly improve the staging of primary cervical cancers. Indeed, the disease progresses in a 'level by level' fashion to regional nodes through the lymphatic channels, and also to extra-nodal sites via the hematogenous stream. Additionally, the sub-optimal efficacy of routine radiological protocols, while new combined therapies are proving to be more efficient, stresses the need for alternative staging procedures. Current data suggest that LM/SL accurately reflects the regional lymph node status in early stage cervical cancers, and thus could avoid unnecessary complete lymphadenectomies. Also, whole body (18)FDG PET may provide valuable insights on extra-pelvic and distant tumor spreading, with a significant impact on treatment choices. If these promising results are confirmed on large controlled trials, LM/SL and (18)FDG PET imaging could be incorporated in the routine staging work-up of primary cervical cancers. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.
http://hdl.handle.net/2268/5521

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
Belhocine et al, Critical Reviews in Oncology 2003.pdfNo commentaryPublisher postprint350.58 kBRequest copy

Additional material(s):

File Commentary Size Access
Restricted access
Belhocine et al, Critical Reviews in Oncology 2003.pdfnull350.58 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.