ORBi: Lenoir Sandrine - New antibacterial cationic surfactants prepared by Atom Transfer Radical Polymerization

Reference : New antibacterial cationic surfactants prepared by Atom Transfer Radical Polymerization


	Document type :	Scientific journals : Article
	Discipline(s) :	Physical, chemical, mathematical & earth Sciences : Chemistry Engineering, computing & technology : Materials science & engineering
	To cite this reference:	http://hdl.handle.net/2268/5474

Title :	New antibacterial cationic surfactants prepared by Atom Transfer Radical Polymerization
Language :	English
Author, co-author :	Lenoir, Sandrine [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
	Pagnoulle, Christophe [Physiol S.A., Liège, Belgium > > > >]
	Detrembleur, Christophe [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
	Galleni, Moreno [University of Liège (ULg) > Département des sciences de la vie > Macromolécules biologiques, Centre d’Ingénierie des Protéines > >]
	Jérôme, Robert [University of Liège (ULg) > Department of Chemistry > Center for Education and Research on Macromolecules (CERM) > >]
Publication date :	1-Feb-2006
Journal title :	Journal of Polymer Science. Part A-1, Polymer Chemistry
Publisher :	Wiley Interscience
Volume :	44
Issue/season :	3
Pages :	1214-1224
Audience :	International
ISSN :	0449-296X
City :	New York
Country :	NY
Keywords :	[en] antimicrobial polymer
Abstract :	[en] Efficient antibacterial surfactants have been prepared by the quaternization of the amino groups of poly(ethylene-co-butylene)-b-poly[2-(dimethylamino)ethylmethacrylate] (PEB-b-PDMAEMA) diblock copolymers by octyl bromide. The diblock copolymers have been synthesized by ATRP of 2-(dimethylamino)ethylmethacrylate (DMAEMA) initiated by an activated bromide-end-capped poly(ethylene-co-butylene). In the presence of CuBr, 1,4,7,10,10-hexamethyl-triethylenetetramine (HMTETA), and toluene at 50 °C, the initiation is slow in comparison with propagation. This situation has been improved by the substitution of CuCl for CuBr, all the other conditions being the same. Finally, the addition of an excess of CuCl2 (deactivator) to the CuCl/HMTETA catalyst is very beneficial in making the agreement between the theoretical and experimental number-average molecular weights excellent. The antibacterial activity of PEB-b-PDMAEMA quaternized by octyl bromide has been assessed against bacteria and is comparable to the activity of a commonly used disinfectant, that is, benzalkonium chloride.
Research units :	Center for Education and Research on Macromolecules (CERM)
Funders :	The European Union in the frame of the project ‘‘Specialty Antimicrobial Polymeric Materials’’ ; Politique Scientifique Fédérale (Belgique) = Belgian Federal Science Policy ; Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Target :	Researchers
Permalink :	http://hdl.handle.net/2268/5474
DOI :	10.1002/pola.21229
Other URL :	http://www3.interscience.wiley.com/cgi-bin/fulltext/112220812/PDFSTART

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