Reference : Intratissular Lymphaticovenous Anastomoses Demonstrated by Perioperative Intramuscula...
Scientific journals : Article
Human health sciences : Radiology, nuclear medicine & imaging
http://hdl.handle.net/2268/5240
Intratissular Lymphaticovenous Anastomoses Demonstrated by Perioperative Intramuscular Injection of 99mtc-Colloids
English
Heymans, Olivier [> > > >]
Fallais, Charles mailto [Université de Liège - ULg > Département de pharmacie > Analyse des médicaments >]
Hustinx, Roland mailto [Université de Liège - ULg > Département des sciences cliniques > Médecine nucléaire]
2006
Lymphatic Research and Biology
Mary Ann Liebert, Inc.
4
1, Spring
29-33
Yes (verified by ORBi)
International
1539-6851
[en] BACKGROUND: The existence of intratissular lymphaticovenous anastomoses has often been suggested, but it has never been demonstrated. This study aims at demonstrating the presence of such anastomoses. METHODS AND RESULTS: The free flap model was used to investigate the drainage of radiolabeled colloid particles whose size prevents direct passage to the blood vessels. The tracer was injected into the muscle or the skin during the surgical procedure. Blood samples were sequentially drawn from the venous pedicle over the 30 minutes that followed the tracer injection. The blood samples were counted using a gamma well-counter. In all 14 patients, the venous blood radioactivity steadily increased over time. Radiochemical analyses performed on the blood samples demonstrated that the radioactivity is related to the labeled colloids and not to free pertechnetate. Planar imaging performed 24 hours after the surgical procedure showed a significant liver uptake, and no accumulation in the area of normal lymphatic relays. CONCLUSIONS: As, in the free flap model, there is no lymphatic drainage through the classical pathways whatsoever, and since the size of the radiolabeled particles prevents them from directly entering the blood stream, the results strongly suggest the presence of functional intratissular lymphovenous anastomoses.
http://hdl.handle.net/2268/5240

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
Heymans O et al, Lymphatic Research and Biol 2006.pdfNo commentaryPublisher postprint142.09 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.