Reference : Maladie de Horton et atteintes artérielles extra-temporales: utilité de la tomographie p...
Scientific journals : Article
Human health sciences : General & internal medicine
http://hdl.handle.net/2268/5216
Maladie de Horton et atteintes artérielles extra-temporales: utilité de la tomographie par émission de positons au 18FDG. A propos de trois observations et d’une revue de la littérature.
French
[en] Horton's disease and extra-temporal vessel locations: role of 18FDG PET scan. Report of 3 cases and review of the literature
Belhocine, Tarik [> > > >]
Kaye, Olivier [> > > >]
Delanaye, Pierre mailto [Centre Hospitalier Universitaire de Liège - CHU > > Néphrologie >]
Corman, Vincianne [> > > >]
Baghaie, M. [> > > >]
Deprez, Manuel mailto [Université de Liège - ULg > Département des sciences cliniques > Neuropathologie >]
Daenen, Frédéric [Centre Hospitalier Universitaire de Liège - CHU > > Médecine nucléaire >]
De Barsy, C. [> > > >]
Beckers, Catherine mailto [Centre Hospitalier Universitaire de Liège - CHU > > Médecine nucléaire >]
Gomez, P. [> > > >]
Hustinx, Roland mailto [Université de Liège - ULg > Département des sciences cliniques > Médecine nucléaire]
Foidart-Willems, J. [> > > >]
Demonty, Jean mailto [Centre Hospitalier Universitaire de Liège - CHU > > Maladies infectieuses et médecine interne générale >]
Malaise, Michel mailto [Université de Liège - ULg > Département des sciences cliniques > Rhumatologie]
Rigo, Pierre mailto [Université de Liège - ULg > Département des sciences de la motricité > Pathologie générale et médecine nucléaire >]
Jul-2002
Revue de Médecine Interne
Editions Scientifiques Medicales Elsevier
23
7
584-591
Yes (verified by ORBi)
International
0248-8663
Paris Cedex 15
[en] Horton's disease ; giant cell arteritis ; vasculitis ; positron emission tomography ; F-18-fluorodeoxyglucose
[en] Increased glucose metabolism detected by (18)FDG PET imaging in unsuspected extra-temporal vessels locations of Horton's disease. Clinical observations and review of literature. Purpose. - We report three cases of Horton's disease, in which F18-Fluorine-2-Deoxy-D-Glucose ((18)FDG) positron emission tomography (PET) demonstrated a clinically unsuspected extra-cranial vessels hypermetabolism. Methods. - Fully corrected whole-body PET was performed in three patients (two women, one man) for exploring a marked inflammatory syndrome. Scanning was acquired 60 min after i.v. injection of 222 MBq of (18)FDG in average. Results. - In two patients with histologically proven Horton's disease, PET alone showed increased glucose metabolism involving the carotid and sub-clavian arteries as well as the ascending aorta, aortic arch, thoracic and abdominal aorta, and the iliac and femoral arteries. In the third patient, by detecting cervical, thoracic and abdominal vessel hypermetabolism, PET non-invasively contributed to the diagnosis of giant cell arteritis. All patients had complete clinical and biological response to corticoids. PET controls performed 3- to 6-months post-treatment, confirmed the disappearance of the metabolic stigma. Conclusion. - (18)FDG PET may show an increased glucose metabolism in asymptomatic extra-cranial vessels locations of Horton's arteritis. If these observations are confirmed on controlled trials, PET could be particularly useful for non-invasive diagnosing, staging and monitoring atypical clinical forms of Horton's disease. The metabolic imaging could also contribute to a better understanding of the pathogenesis of GCA. (C) 2002 Editions scientifiques et medicales Elsevier SAS.
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/5216
http://www.elsevier.com/wps/find/journaldescription.cws_home/524797/description#description
All our thank to Elsevier

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