Reference : Maladie de Horton et atteintes arterielles extratemporales: utilite de la tomographie...
Scientific journals : Article
Human health sciences : Neurology
http://hdl.handle.net/2268/62381
Maladie de Horton et atteintes arterielles extratemporales: utilite de la tomographie par emission de positons au 18FDG. A propos de trois observations et d'une revue de la litterature
French
[en] Horton's disease and extra-temporal vessel locations: role of 18FDG PET scan. Report of 3 cases and review of the literature
Belhocine, Tarik [> > > >]
Kaye, Olivier [> >]
Delanaye, Pierre mailto [Centre Hospitalier Universitaire de Liège - CHU > > Néphrologie >]
Corman, Vincianne [> > > >]
Baghaie, M. [> > > >]
Deprez, Manuel [Université de Liège - ULg > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques >]
Daenen, Frédéric [Centre Hospitalier Universitaire de Liège - CHU > > Médecine nucléaire >]
De Barsy, C. [> > > >]
Beckers, Catherine mailto [Centre Hospitalier Universitaire de Liège - CHU > > Médecine nucléaire >]
Gomez, P. [> > > >]
Hustinx, Roland mailto [Centre Hospitalier Universitaire de Liège - CHU > > Médecine nucléaire >]
Foidart-Willems, Jacqueline mailto [Centre Hospitalier Universitaire de Liège - CHU > > Médecine nucléaire >]
Demonty, Jean mailto [Centre Hospitalier Universitaire de Liège - CHU > > Maladies infectieuses et médecine interne générale >]
Malaise, Michel mailto [Centre Hospitalier Universitaire de Liège - CHU > > Rhumatologie >]
Rigo, Pierre mailto [Université de Liège - ULg > Département des sciences de la motricité > Pathologie générale et médecine nucléaire >]
2002
Revue de Médecine Interne
Elsevier
23
7
584-91
Yes (verified by ORBi)
International
0248-8663
Paris
France
[en] Aged ; giant cell arteritis ; Horton's disease ; Aorta/pathology ; vasculitis ; Carotid Arteries/pathology ; positron emission tomography ; Female ; F-18-fluorodeoxyglucose ; Fluorodeoxyglucose F18/diagnostic use ; Giant Cell Arteritis/physiopathology/radionuclide imaging ; Glucose/metabolism ; Humans ; Male ; Middle Aged ; Radiopharmaceuticals/diagnostic use ; Subclavian Artery/pathology ; Tomography, Emission-Computed
[en] PURPOSE: We report three cases of Horton's disease, in which F18-Fluorine-2-Deoxy-D-Glucose (18FDG) positron emission tomography (PET) demonstrated a clinically unsuspected extra-cranial vessels hypermetabolism. METHODS: Fully corrected whole-body PET was performed in three patients (two women, one man) for exploring a marked inflammatory syndrome. Scanning was acquired 60 min after i.v. injection of 222 MBq of 18FDG in average. RESULTS: In two patients with histologically proven Horton's disease, PET alone showed increased glucose metabolism involving the carotid and sub-clavian arteries as well as the ascending aorta, aortic arch, thoracic and abdominal aorta, and the iliac and femoral arteries. In the third patient, by detecting cervical, thoracic and abdominal vessel hypermetabolism, PET non-invasively contributed to the diagnosis of giant cell arteritis. All patients had complete clinical and biological response to corticoids. PET controls performed 3- to 6-months post-treatment, confirmed the disappearance of the metabolic stigma. CONCLUSION: 18FDG PET may show an increased glucose metabolism in asymptomatic extracranial vessels locations of Horton's arterities. If these observations are confirmed on controlled trials, PET could be particularly useful for non-invasive diagnosing, staging and monitoring atypical clinical forms of Horton's disease. The metabolic imaging could also contribute to a better understanding of the pathogenesis of GCA.
Researchers ; Professionals
http://hdl.handle.net/2268/62381
also: http://hdl.handle.net/2268/5216
http://www.elsevier.com/wps/find/journaldescription.cws_home/524797/description#description
All our thank to Elsevier

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Open access
Maladie de Horton et atteintes arterielles extratemporales utilite de la tomographie par emission de positons au 18FDG A propos de trois observations et d'une revue de .pdfAuthor postprint905.59 kBView/Open

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.