Reference : Sleep-related hippocampo-cortical interplay during emotional memory recollection.
Scientific journals : Article
Social & behavioral sciences, psychology : Neurosciences & behavior
http://hdl.handle.net/2268/5184
Sleep-related hippocampo-cortical interplay during emotional memory recollection.
English
Sterpenich, Virginie [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Albouy, Geneviève [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Boly, Mélanie mailto [Université de Liège - ULg > Département des sciences cliniques > Neurologie >]
Vandewalle, Gilles mailto [> > > >]
Darsaud, Annabelle [> > > >]
Balteau, Evelyne mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Dang Vu, Thien Thanh [Université de Liège - ULg > Département des sciences cliniques > Neurologie >]
Desseilles, Martin mailto [Université de Liège - ULg > Département des sciences cliniques > Psychiatrie et psychologie médicale >]
D'Argembeau, Arnaud mailto [Université de Liège - ULg > Département des sciences cognitives > Psychopathologie cognitive >]
Gais, Steffen [> > > >]
Rauchs, Geraldine [> > > >]
Schabus, Manuel [> > > >]
Degueldre, Christian mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Luxen, André mailto [Université de Liège - ULg > Département de chimie (sciences) > Chimie organique de synthèse - Centre de recherches du cyclotron >]
Collette, Fabienne mailto [Université de Liège - ULg > Département des sciences cognitives > Neuropsychologie - Département des sciences cognitives >]
Maquet, Pierre mailto [Centre Hospitalier Universitaire de Liège - CHU > > Neurologie Sart Tilman >]
2007
PLoS Biology
Public Library of Science
5
11
e282
Yes (verified by ORBi)
International
1545-7885
San Francisco
CA
[en] Adult ; Behavior/physiology ; Cerebral Cortex/anatomy & histology/physiology ; Emotions/physiology ; Female ; Hippocampus/anatomy & histology/physiology ; Humans ; Magnetic Resonance Imaging ; Male ; Memory/physiology ; Mental Recall/physiology ; Sleep/physiology ; Sleep Deprivation
[en] Emotional events are usually better remembered than neutral ones. This effect is mediated in part by a modulation of the hippocampus by the amygdala. Sleep plays a role in the consolidation of declarative memory. We examined the impact of sleep and lack of sleep on the consolidation of emotional (negative and positive) memories at the macroscopic systems level. Using functional MRI (fMRI), we compared the neural correlates of successful recollection by humans of emotional and neutral stimuli, 72 h after encoding, with or without total sleep deprivation during the first post-encoding night. In contrast to recollection of neutral and positive stimuli, which was deteriorated by sleep deprivation, similar recollection levels were achieved for negative stimuli in both groups. Successful recollection of emotional stimuli elicited larger responses in the hippocampus and various cortical areas, including the medial prefrontal cortex, in the sleep group than in the sleep deprived group. This effect was consistent across subjects for negative items but depended linearly on individual memory performance for positive items. In addition, the hippocampus and medial prefrontal cortex were functionally more connected during recollection of either negative or positive than neutral items, and more so in sleeping than in sleep-deprived subjects. In the sleep-deprived group, recollection of negative items elicited larger responses in the amygdala and an occipital area than in the sleep group. In contrast, no such difference in brain responses between groups was associated with recollection of positive stimuli. The results suggest that the emotional significance of memories influences their sleep-dependent systems-level consolidation. The recruitment of hippocampo-neocortical networks during recollection is enhanced after sleep and is hindered by sleep deprivation. After sleep deprivation, recollection of negative, potentially dangerous, memories recruits an alternate amygdalo-cortical network, which would keep track of emotional information despite sleep deprivation.
Researchers
http://hdl.handle.net/2268/5184
10.1371/journal.pbio.0050282

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