Reference : La pyknocytose infantile : une anemie neonatale mal connue a propos de 5cas.
Scientific journals : Article
Human health sciences : Pediatrics
La pyknocytose infantile : une anemie neonatale mal connue a propos de 5cas.
[en] Infantile pyknocytosis: A rare form of neonatal hemolytic anemia. 5 case-studies.
Limme, Boris [Université de Liège - ULg > > Pédiatrie >]
Dresse, Marie-Françoise mailto [Centre Hospitalier Universitaire de Liège - CHU > > Pédiatrie CHR >]
Ketelslegers, O. [> > > >]
Rigo, Vincent mailto [Centre Hospitalier Universitaire de Liège - CHU > > Néonatologie >]
Hoyoux, Claire [> >]
Archives de Pédiatrie
Yes (verified by ORBi)
[en] Anemia ; Infantile pyknocytosis ; hemolysis
[en] Infantile pyknocytosis (IP) is a rare hematological entity of newborns. It is a form of hemolytic anemia with unusual red cell morphology: the red blood cells are distorted, irregular, and small with many projections. Spontaneous resolution usually occurs by 4-6months of age. OBSERVATION: We describe the clinical features and biological parameters of 5 cases of IP. The first symptoms were always early jaundice, which required phototherapy. Anemia was severe in all babies and red blood cell transfusion was needed. CONCLUSION: IP is a rare cause of neonatal anemia whose diagnosis is based on a careful peripheral blood smear examination. In our study, anemia was severe and required red blood cell transfusion. Ethnic specificity and familial occurrence are reported in our experience.

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