Article (Scientific journals)
Neuropsychiatric syndromes in dementia - Results from the European Alzheimer Disease Consortium: Part I
Aalten, Pauline; Verhey, Frans R. J.; Boziki, Marina et al.
2007In Dementia and Geriatric Cognitive Disorders, 24 (6), p. 457-463
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Keywords :
neuropsychiatric syndromes; neuropsychiatric inventory; factor analysis; Alzheimer's disease; dementia; subsyndromes
Abstract :
[en] Background/Aims: The aim of this study was to identify neuropsychiatric subsyndromes of the Neuropsychiatric Inventory in a large sample of outpatients with Alzheimer's disease (AD). Methods: Cross-sectional data of 2,354 patients with AD from 12 centres from the European Alzheimer's Disease Consortium were collected. Principal component analysis was used for factor analysis. Results: The results showed the presence of 4 neuropsychiatric subsyndromes: hyperactivity, psychosis, affective symptoms and apathy. The subsyndrome apathy was the most common, occurring in almost 65% of the patients. Conclusion: This large study has provided additional robust evidence for the existence of neuropsychiatric subsyndromes in AD. Copyright (c) 2007 S. Karger AG, Basel.
Disciplines :
Sociology & social sciences
Geriatrics
Neurology
Author, co-author :
Aalten, Pauline;  Maastricht University Hospital > Alzheimer Centre Limburg > Department of Psychiatry and Neuropsychology
Verhey, Frans R. J.;  Maastricht University Hospital > Alzheimer Centre Limburg > Department of Psychiatry and Neuropsychology
Boziki, Marina
Bullock, Roger
Byrne, Eleanor Jane
Camus, Vincent
Caputo, Miriam
Collins, Debby
De Deyn, Peter Paul
Elina, Kazi
Frisoni, Giovanni
Girtler, Nicola
Holmes, Clive
Hurt, Catherine
Marriott, Anna
Mecocci, Patrizia
Nobili, Flavio
Ousset, Pierre Jean
Reynish, Emma
Salmon, Eric  ;  Université de Liège - ULiège > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn.
Tsolaki, Magda
Vellas, Bruno
Robert, Philippe H.
More authors (13 more) Less
Language :
English
Title :
Neuropsychiatric syndromes in dementia - Results from the European Alzheimer Disease Consortium: Part I
Publication date :
2007
Journal title :
Dementia and Geriatric Cognitive Disorders
ISSN :
1420-8008
eISSN :
1421-9824
Publisher :
Karger, Basel, Switzerland
Volume :
24
Issue :
6
Pages :
457-463
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]
EADC - European Alzheimer's Disease Consortium [BE]
Available on ORBi :
since 28 January 2009

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