Article (Scientific journals)
Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial
Sandor, P. S.; Di Clemente, L.; Coppola, G. et al.
2005In Neurology, 64 (4), p. 713-715
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Abstract :
[en] Riboflavin, which improves energy metabolism similarly to coenzyme Q10 (CoQ10), is effective in migraine prophylaxis. We compared CoQ10 (3 x 100 mg/day) and placebo in 42 migraine patients in a double-blind, randomized, placebo-controlled trial. CoQ10 was superior to placebo for attack-frequency, headache-days and days-with-nausea in the third treatment month and well tolerated; 50%-responder-rate for attack frequency was 14.4% for placebo and 47.6% for CoQ10 (number-needed-to-treat: 3). CoQ10 is efficacious and well tolerated.
Disciplines :
Neurology
Author, co-author :
Sandor, P. S.
Di Clemente, L.
Coppola, G.
Saenger, U.
Fumal, Arnaud ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie CHR
Magis, Delphine ;  Centre Hospitalier Universitaire de Liège - CHU > Neurologie Sart Tilman
Seidel, Laurence  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Informatique médicale et biostatistique
Agosti, R. M.
Schoenen, Jean  ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Neuro-anatomie
Language :
English
Title :
Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial
Publication date :
22 February 2005
Journal title :
Neurology
ISSN :
0028-3878
eISSN :
1526-632X
Publisher :
Lippincott Williams & Wilkins, Philadelphia, United States - Pennsylvania
Volume :
64
Issue :
4
Pages :
713-715
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 28 January 2009

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