No full text
Article (Scientific journals)
Recent advances in prostate cancer metastasis
Waltregny, David; Castronovo, Vincenzo
1996In Tumori Journal, 82 (3, May-Jun), p. 193-204
Peer Reviewed verified by ORBi
 

Files


Full Text
No document available.

Send to



Details



Abstract :
[en] Prostate cancer in men has now surpassed lung cancer as the most frequent non-cutaneous cancer. From a biological perspective, prostate carcinoma is unique among human malignancies in the wide discrepancy that exists between the prevalence of 'latent' cancer, recognizable only histologically, and that of the clinical disease. Histologically detected localized prostate cancers are heterogeneous, with only a small subset having undergone all of the malignant changes required to produce clinically aggressive tumors. Most of these 'latent' carcinoma never become fully malignant and do not threaten the life or well-being of the host. At present, it is not possible to predict which localized cancers will progress to clinically overt disease. Likewise, many patients have underevaluated and unpredictable extent of their prostate carcinoma, thus resulting in inadequate therapeutic strategies. It is clear that we need to identify molecular and/or cellular markers that are able to define the invasive and metastatic potential of prostate cancer on an individual patient basis. Acquisition of metastatic ability is a definitive criterion by which substage localized prostate cancers. Under the light of recent studies designed to identify some of the features associated with the metastatic phenotype of prostate cancer, the authors review recent advances aimed at gaining insight into those factors that may be involved in prostate cancer metastasis.
Disciplines :
Urology & nephrology
Author, co-author :
Waltregny, David  ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Labo de recherche sur les métastases
Castronovo, Vincenzo ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie générale et cellulaire
Language :
English
Title :
Recent advances in prostate cancer metastasis
Publication date :
1996
Journal title :
Tumori Journal
ISSN :
0300-8916
eISSN :
2038-2529
Publisher :
Sage, London, United Kingdom
Volume :
82
Issue :
3, May-Jun
Pages :
193-204
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 24 January 2009

Statistics


Number of views
42 (2 by ULiège)
Number of downloads
0 (0 by ULiège)

Scopus citations®
 
9
Scopus citations®
without self-citations
9

Bibliography


Similar publications



Contact ORBi