Screening for Proteinuria and Chronic Kidney Disease Risk Factors in Kinshasa:A World Kidney Day 2007 Study

[en] Abstract Background: Although screening programs for chronic kidney disease (CKD) may be of great value, these programs are not yet implemented in the Democratic Republic of Congo. This study focused on proteinuria and examined its prevalence in terms of the number needed to screen for the different risk factors of CKD. Such knowledge would guide the utility of population screening to prevent end-stage renal disease. Methods: A cross-sectional survey was conducted in Kinshasa on the Second World Kidney Day. A sample of 3,018 subjects was interviewed and the following measurements were performed: blood pressure, body mass index, glycemia and urine protein. Logistic regression analysis was used to identify determinants of proteinuria. Results: The prevalence of proteinuria was 17.1% (95% CI 15.8–18.6). Other CKD risk factors identified were: hypertension, diabetes mellitus, obesity and metabolic syndrome. To identify 1 case of proteinuria, one would need to screen 4 persons with dia-betes, 5 persons with hypertension, 4 subjects having metabolic syndrome, 5 persons aged 6 72 years and 9 persons without any of the conditions mentioned above. Age, overweight and diabetes were the strongest factors associated with proteinuria. Conclusions: This study indicates that proteinuria and traditional risk factors for CKD are very prevalent in Kinshasa. Realistic policies to stem these conditions should be a public health priority.

Disciplines :

Urology & nephrology

Author, co-author :

Sumaili, Ernest K.; University of Kinshasa- Democratic Republic of Congo > Nephrology Unit

Nseka, Nazaire M.; University of Kinshasa - Democratic Republic of Congo > Nephrology Unit

Lepira, François B.; University of Kinshasa - Democratic Republic of Congo > Nephrology Unit

Krzesinski, Jean-Marie ; Université de Liège - ULiège > Département des sciences cliniques > Néphrologie

Makulo, Jean Robert R.; University of Kinshasa - Democratic Republic of Congo > Nephrology Unit

Bukabau, Justine B.; University of Kinshasa - Democratic Republic of Congo > Nephrology Unit

Nkoy, Josée B.; Saint Joseph Hospital of Kinshasa - Democratic Republic of Congo

Mokoli, Vieux M.; University of Kinshasa - Democratic Republic of Congo > Nephrology Unit

Longokolo, Murielle M.; University of Kinshasa - Democratic Republic of Congo > Nephrology Unit

Owandjalola, Julie A.; University of Kinshasa - Democratic Republic of Congo > Nephrology Unit

Kayembe, Patrick K.; University of Kinshasa - Democratic Republic of Congo > School of Public Health > Medical Epidemiology and Biostatistics Unit

Language :

English

Title :

Screening for Proteinuria and Chronic Kidney Disease Risk Factors in Kinshasa:A World Kidney Day 2007 Study

Publication date :

31 October 2008

Journal title :

Nephron. Clinical Practice

eISSN :

1660-2110

Publisher :

Karger

Volume :

110

Pages :

c220-c228

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 22 January 2009

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