dihydroflavopereirine; sempervirine; cancer cells in culture; antimitotic activity; anhydronium bases; cytology
Abstract :
[en] The cellular effects of dihydroflavopereirine and sempervirine ( two alkaloids isolated from Loganiaceae) are analysed by cytological methods in experimental tumours cultivated in vitro ( B16 mouse melanoma cells, mouse Ehrlich tumour cells ELT). Under some experimental conditions, a certain degree of antimitotic activity is demonstrated and related to the molecular structure.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Bassleer, Roger ; Université de Liège - ULiège > Relations académiques et scientifiques (Médecine)
Clermont, D.
Marnette, J. M.
Caprasse, Maryse
Tits, Monique ; Université de Liège - ULiège > Département de pharmacie > Phytochimie et phytothérapie
Angenot, Luc ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Language :
English
Title :
Effets de la dihydroflavopéreirine et de la sempervirine (alacaloïdes dérivés de la beta-carboline) sur des cellules cancéreuses en culture
Alternative titles :
[en] Effects of dihydroflavopereirine and sempervirine (beta-carbolinium alkaloids) on cancer cells in culture
