[en] The preparation of granules by melt granulation was investigated using a laboratory-scale high-shear mixer (Pellmix PL 1/8) and binary mixtures containing lactose and different lipidic binders, namely, Compritol 888, Cutina HR, or Precirol ATO5.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Evrard, Brigitte ; Université de Liège - ULiège > Département de pharmacie > Pharmacie galénique
Amighi, K.
Beten, D.
Delattre, Luc ; Université de Liège - ULiège > Département de pharmacie > Département de pharmacie
Moes, A. J.
Language :
English
Title :
Influence of Melting and Rheological Properties of Fatty Binders on the Melt Granulation Process in a High-Shear Mixer
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