Reference : Place des anticorps monoclonaux dans le traitement des tumeurs de la tete et du cou.
Scientific journals : Article
Human health sciences : Oncology
http://hdl.handle.net/2268/40916
Place des anticorps monoclonaux dans le traitement des tumeurs de la tete et du cou.
French
[en] Monoclonal antibodies for the treatment of head and neck cancer
Sautois, Brieuc mailto [Centre Hospitalier Universitaire de Liège - CHU > > Oncologie médicale >]
Martin, Marie [Université de Liège - ULg > > Oncologie médicale >]
Demez, Pierre mailto [Centre Hospitalier Universitaire de Liège - CHU > > O.R.L. >]
Piret, Pascal mailto [Centre Hospitalier Universitaire de Liège - CHU > > Radiothérapie >]
Devillers, David [ > > ]
Moreau, Pierre mailto [Université de Liège - ULg > > O.R.L. >]
2009
Revue Médicale de Liège
Hopital de Baviere
64
5-6
284-6
Yes (verified by ORBi)
National
0370-629X
Liège
Belgique
[en] Antibodies, Monoclonal/therapeutic use ; Antineoplastic Agents/therapeutic use ; Head and Neck Neoplasms/drug therapy ; Humans ; Receptor, Epidermal Growth Factor/antagonists & inhibitors
[en] Monoclonal antibodies are now part of the armamentarium available for the treatment of head and neck cancer. Cetuximab, a monoclonal antibody targeting EGFR, improves overall survival as compared with radiotherapy alone as radical treatment of locally advanced head and neck cancer. It is now reimbursed in Belgium after multidisciplinary discussion if cisplatin is contra-indicated. In the metastatic setting adding cetuximab to platinum based chemotherapy improves overall survival as compared with chemotherapy alone, a first-time event over a 30-year period, unfortunately not yet accessible to the Belgian patients. Other monoclonal antibodies targeting EGFR or VEGF are also currently under investigation while cetuximab is being explored in the induction, the maintenance or the post-operative radiotherapy settings.
http://hdl.handle.net/2268/40916

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