Article (Scientific journals)
Place des anticorps monoclonaux dans le traitement des tumeurs de la tete et du cou.
Sautois, Brieuc; Martin, Marie; Demez, Pierre et al.
2009In Revue Médicale de Liège, 64 (5-6), p. 284-6
Peer reviewed
 

Files


Full Text
Sautois atc monoclonaux HetN[1].pdf
Publisher postprint (292.62 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Antibodies, Monoclonal/therapeutic use; Antineoplastic Agents/therapeutic use; Head and Neck Neoplasms/drug therapy; Humans; Receptor, Epidermal Growth Factor/antagonists & inhibitors
Abstract :
[en] Monoclonal antibodies are now part of the armamentarium available for the treatment of head and neck cancer. Cetuximab, a monoclonal antibody targeting EGFR, improves overall survival as compared with radiotherapy alone as radical treatment of locally advanced head and neck cancer. It is now reimbursed in Belgium after multidisciplinary discussion if cisplatin is contra-indicated. In the metastatic setting adding cetuximab to platinum based chemotherapy improves overall survival as compared with chemotherapy alone, a first-time event over a 30-year period, unfortunately not yet accessible to the Belgian patients. Other monoclonal antibodies targeting EGFR or VEGF are also currently under investigation while cetuximab is being explored in the induction, the maintenance or the post-operative radiotherapy settings.
Disciplines :
Oncology
Author, co-author :
Sautois, Brieuc  ;  Centre Hospitalier Universitaire de Liège - CHU > Oncologie médicale
Martin, Marie ;  Université de Liège - ULiège > Oncologie médicale
Demez, Pierre ;  Centre Hospitalier Universitaire de Liège - CHU > O.R.L.
Piret, Pascal ;  Centre Hospitalier Universitaire de Liège - CHU > Radiothérapie
Devillers, David
Moreau, Pierre ;  Université de Liège - ULiège > O.R.L.
Language :
French
Title :
Place des anticorps monoclonaux dans le traitement des tumeurs de la tete et du cou.
Alternative titles :
[en] Monoclonal antibodies for the treatment of head and neck cancer
Publication date :
2009
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Hopital de Baviere, Liège, Belgium
Volume :
64
Issue :
5-6
Pages :
284-6
Peer reviewed :
Peer reviewed
Available on ORBi :
since 03 March 2010

Statistics


Number of views
161 (12 by ULiège)
Number of downloads
5 (1 by ULiège)

Scopus citations®
 
1
Scopus citations®
without self-citations
0

Bibliography


Similar publications



Contact ORBi