Reference : Fast Production of Highly Reactive No-Carrier-Added [18F]Fluoride for the Labeling of...
Scientific journals : Article
Physical, chemical, mathematical & earth Sciences : Chemistry
http://hdl.handle.net/2268/40483
Fast Production of Highly Reactive No-Carrier-Added [18F]Fluoride for the Labeling of Radiopharmaceuticals
English
Lemaire, Christian mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Aerts, Joël mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Voccia, Samuel [> >]
Libert, Lionel mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Mercier, Frédéric mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Goblet, David mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Plenevaux, Alain mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Luxen, André mailto [Université de Liège - ULg > Département de chimie (sciences) > Chimie organique de synthèse - Centre de recherches du cyclotron >]
2010
Angewandte Chemie (International ed. in English)
Wiley-VCH Verlag Gmbh
49
1-5
Yes (verified by ORBi)
International
1433-7851
1521-3773
Weinheim
Germany
[en] The 18F labeling of radiopharmaceuticals requires nearly anhydrous solutions of [18F]fluoride.
Aqueous K2CO3 is generally used to elute [18F]fluoride from an anion-exchange resin. Replacing aqueous K2CO3 with strong organic bases, such as the phosphazene base P2Et enabled the recovery of highly reactive [18F]fluoride and avoided the azeotropic evaporation of water, which is
very difficult on a microchip device.
Centre de Recherches du Cyclotron - CRC
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/40483

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