Reference : Sleep promotes the neural reorganization of remote emotional memory.
Scientific journals : Article
Human health sciences : Neurology
http://hdl.handle.net/2268/40293
Sleep promotes the neural reorganization of remote emotional memory.
English
Sterpenich, Virginie [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Albouy, Genevieve [> > > >]
Darsaud, Annabelle [> > > >]
Schmidt, Christina mailto [Université de Liège - ULg > Département des sciences cognitives > Neuropsychologie >]
Vandewalle, Gilles mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Dang Vu, Thien Thanh [Université de Liège - ULg > Centre de Recherches du Cyclotron - Département des sciences cliniques > Neurologie > > >]
Desseilles, Martin [Université de Liège - ULg > Centre de Recherches du cyclotron - Département des sciences cliniques > Psychiatrie et psychologie médicale > > >]
Phillips, Christophe [Université de Liège - ULg > > Centre de recherches du cyclotron - Dép. d'électric., électron. et informat. (Inst.Montefiore) >]
Degueldre, Christian [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Balteau, Evelyne [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Collette, Fabienne [Université de Liège - ULg > Centre de Recherches du Cyclotron - Département des sciences cognitives > Neuropsychologie - Département des sciences cognitives > > >]
Luxen, André [Université de Liège - ULg > Centre de Recherches du Cyclotron - Département de chimie (sciences) > Chimie organique de synthèse - Centre de recherches du cyclotron > > >]
Maquet, Pierre mailto [Université de Liège - ULg > > Centre de recherches du cyclotron - Département des sciences cliniques >]
Apr-2009
Journal of Neuroscience
Society for Neuroscience
29
16
5143-52
Yes (verified by ORBi)
International
0270-6474
1529-2401
Washington
DC
[en] Adolescent ; Adult ; Emotions/physiology ; Female ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Memory/physiology ; Mental Recall/physiology ; Neurons/physiology ; Sleep/physiology ; Sleep Deprivation/physiopathology ; Time Factors ; Young Adult
[en] Sleep promotes memory consolidation, a process by which fresh and labile memories are reorganized into stable memories. Emotional memories are usually better remembered than neutral ones, even at long retention delays. In this study, we assessed the influence of sleep during the night after encoding onto the neural correlates of recollection of emotional memories 6 months later. After incidental encoding of emotional and neutral pictures, one-half of the subjects were allowed to sleep, whereas the others were totally sleep deprived, on the first postencoding night. During subsequent retest, functional magnetic resonance imaging sessions taking place 3 d and 6 months later, subjects made recognition memory judgments about the previously studied and new pictures. Between these retest sessions, all participants slept as usual at home. At 6 month retest, recollection was associated with significantly larger responses in subjects allowed to sleep than in sleep-deprived subjects, in the ventral medial prefrontal cortex (vMPFC) and the precuneus, two areas involved in memory retrieval, as well as in the extended amygdala and the occipital cortex, two regions the response of which was modulated by emotion at encoding. Moreover, the functional connectivity was enhanced between the vMPFC and the precuneus, as well as between the extended amygdala, the vMPFC, and the occipital cortex in the sleep group relative to the sleep-deprived group. These results suggest that sleep during the first postencoding night profoundly influences the long-term systems-level consolidation of emotional memory and modifies the functional segregation and integration associated with recollection in the long term.
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS ; fondation Médicale reine Elisabeth ; Poles d’Attraction Interuniversitaires Grant P5/04
http://hdl.handle.net/2268/40293
10.1523/JNEUROSCI.0561-09.2009

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