Article (Scientific journals)
Le cas clinique du mois. Reaction de rappel d'irradiation induite par l'administration de cyclophosphamide.
Mievis, Carole; Jansen, Nicolas; Schleich, FLorence et al.
2009In Revue Médicale de Liège, 64 (4), p. 179-81
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Keywords :
Adenocarcinoma/drug therapy/radiotherapy/secondary/therapy; Administration, Oral; Antineoplastic Agents, Alkylating/administration & dosage/adverse effects; Bone Neoplasms/drug therapy/radiotherapy/secondary/therapy; Chemotherapy, Adjuvant/adverse effects; Combined Modality Therapy; Cyclophosphamide/administration & dosage/adverse effects; Humans; Male; Middle Aged; Palliative Care; Prostatic Neoplasms/drug therapy/pathology/radiotherapy/therapy; Radiodermatitis/chemically induced/etiology; Radiotherapy, Adjuvant/adverse effects
Abstract :
[en] Radiation recall dermatitis is an inflammatory skin reaction occurring in a previously irradiated field following the delivery of a promoting agent. It has been described after a number of antineoplastic agents such as gemcitabine, taxanes, anthracyclines. We report the case of a 50-year-old man with metastatic prostate cancer who developed two consecutive radiation recall dermatitis episodes triggered by oral cyclophosphamide. They occurred 4 to 5 weeks after palliative radiotherapy on bone metastasis. Spontaneous resolution was observed within 6 weeks after discontinuation of cyclophosphamide and with local supportive care. To our knowledge this is the first reported case of radiation recall dermatitis after oral cyclophosphamide.
Disciplines :
Oncology
Author, co-author :
Mievis, Carole ;  Centre Hospitalier Universitaire de Liège - CHU > Radiothérapie
Jansen, Nicolas ;  Centre Hospitalier Universitaire de Liège - CHU > Radiothérapie
Schleich, FLorence ;  Centre Hospitalier Universitaire de Liège - CHU > Pneumologie-Allergologie
Gennigens, Christine  ;  Centre Hospitalier Universitaire de Liège - CHU > Oncologie médicale
Rorive, Andrée ;  Centre Hospitalier Universitaire de Liège - CHU > Oncologie médicale
Jerusalem, Guy  ;  Centre Hospitalier Universitaire de Liège - CHU > Oncologie médicale
Fillet, Georges ;  Centre Hospitalier Universitaire de Liège - CHU > Hématologie clinique
Sautois, Brieuc  ;  Centre Hospitalier Universitaire de Liège - CHU > Oncologie médicale
Language :
French
Title :
Le cas clinique du mois. Reaction de rappel d'irradiation induite par l'administration de cyclophosphamide.
Alternative titles :
[de] Radiation recall dermatitis after oral cyclophosphamide
Publication date :
2009
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Hopital de Baviere, Liège, Belgium
Volume :
64
Issue :
4
Pages :
179-81
Peer reviewed :
Peer reviewed
Available on ORBi :
since 24 February 2010

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