Reference : Preparations and characterisations of semi-solid formulations containing a hydrophilic d...
Scientific congresses and symposiums : Poster
Human health sciences : Pharmacy, pharmacology & toxicology
http://hdl.handle.net/2268/39659
Preparations and characterisations of semi-solid formulations containing a hydrophilic drug for vaginal administration
English
[fr] Préparations et caractérisations de formulations semi-solides contenant un principe actif hydrophile pour l'administration vaginale
Coia, Isabelle mailto [Université de Liège - ULg > Département de pharmacie > Pharmacie galénique >]
Evrard, Brigitte mailto [Université de Liège - ULg > Département de pharmacie > Pharmacie galénique >]
Piette, Marie mailto [Université de Liège - ULg > Département de pharmacie > Pharmacie galénique >]
1-Apr-2009
A0
No
International
Biomedica
du 1 avril 2009 au 2 avril 2009
Biomedica
Liège
Belgique
[en] The purpose of this study is to demonstrate the effect of different types of semi-solid formulations (aqueous gels, liquid jellified emulsions and hydrophilic or lipophilic creams) for vaginal administration on the release kinetic of a hydrophilic drug. This drug is an acidic and hydrophilic (log P (octanol/water) = -3.3) molecule with an aqueous solubility upper than 170mg/ml at pH 6-8.

The formulations characterisations consisted in the in vitro evaluation of the drug release kinetic and the measure of all formulations viscosity as well as the creams stability and emulsions droplets size.
Région wallonne : Direction générale des Technologies, de la Recherche et de l'Energie - DGTRE
http://hdl.handle.net/2268/39659

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