Article (Scientific journals)
Syndrome de Hoffmann aux urgences
Kaux, Jean-François; Castermans, Caroline; Delmotte, Philippe et al.
2007In Annales de Réadaptation et de Médecine Physique, 50 (5), p. 310-2
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Keywords :
Hoffmann's syndrome; myopathy; hypothyroidism
Abstract :
[en] We report a case of hypothyroid myopathy, or Hoffmann syndrome, in a 31-year-old man who presented to the emergency department with asthenia, muscular pain, cramps, and joint pain. Tests revealed increased creatine phosphokinase level (8102 U/L) and severe hypothyroidism (content of T4=3.8 pg/ml, T3=1.3 pg/ml, and thyrotropin stimulating hormone>150 microU/ml). Other causes of myopathy were excluded by anamnestic investigation and paraclinical exam. Treatment was begun with thyroid hormones (from 75 to 175 microg) and good clinical evolution was rapid. The pathophysiology of hypothyroid myopathy, clinical aspects and pathologic anatomic elements are described. The exact etiology of hypothyroidism must be known because some pathologic features are benign and treatment can have good results, whereas others, such as cancer, have worse prognosis.
Disciplines :
Endocrinology, metabolism & nutrition
Rheumatology
Orthopedics, rehabilitation & sports medicine
General & internal medicine
Author, co-author :
Kaux, Jean-François  ;  Université de Liège - ULiège > Département des sciences de la motricité > Médecine physique et réadaptation fonctionnelle
Castermans, Caroline;  Centre Hospitalier Régionale de la Citadelle (Liège) - CHR CITADELLE > Médecine Physique > Rhumatologie
Delmotte, Philippe;  Centre Hospitalier Régionale de la Citadelle (Liège) - CHR CITADELLE > Médecine interne > Endocrinologie
Bex, Michèle;  Centre Hospitalier Régionale de la Citadelle (Liège) - CHR CITADELLE > Médecine physique > Médecine physique
Language :
French
Title :
Syndrome de Hoffmann aux urgences
Alternative titles :
[en] Hoffmann Syndrome Presenting to the Emergency Department
Publication date :
June 2007
Journal title :
Annales de Réadaptation et de Médecine Physique
ISSN :
0168-6054
Publisher :
Elsevier, Netherlands
Volume :
50
Issue :
5
Pages :
310-2
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 08 January 2009

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