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Cytofluorometric analysis of prostate cancer specimens: Histological and clinical correlations
de Leval, Laurence; Waltregny, David; Greimers, Roland et al.
1994In Acta Urologica Belgica, 62, p. 37-43
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Keywords :
prostate cancer; FACS; DNA
Abstract :
[en] DNA histograms were oblained by flow cytometry for 39 human prostate carcinomas (27 total proslatectomy specimens, 5 biopsies and 7 transuretral resections). The study was performed on formalin-fixed and paraffin-embedded. material. In this report, ploidy index did not seem to be a good marker of prognosis as no significant variation in ploidy was found neither among the different stages nor among the different Gleason categories. Proliferative index of the tumors seemed to be a more sensitive parameter; a significant relation was observed between proliferative index and stage of the tumor. The authors discuss these results under the light of previously reported observations.
Disciplines :
Biochemistry, biophysics & molecular biology
Anatomy (cytology, histology, embryology...) & physiology
Laboratory medicine & medical technology
Author, co-author :
de Leval, Laurence ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques - Département des sciences biomédicales et précliniques
Waltregny, David  ;  Université de Liège - ULiège > Département des sciences cliniques > Urologie - GIGA-R : Labo de recherche sur les métastases
Greimers, Roland ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Boniver, Jacques ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Language :
English
Title :
Cytofluorometric analysis of prostate cancer specimens: Histological and clinical correlations
Publication date :
January 1994
Event name :
2nd Euregional Oncology meeting
Event place :
Liège, Belgium
Event date :
Janvier 1995
By request :
Yes
Audience :
International
Journal title :
Acta Urologica Belgica
ISSN :
0001-7183
Publisher :
Acta Medica Belgica, Bruxelles, Belgium
Volume :
62
Pages :
37-43
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 23 May 2010

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