Reference : A propos des transformations de la strychnine et (à propos des principes actifs) des Str...
Scientific journals : Short communication
Physical, chemical, mathematical & earth Sciences : Chemistry
Human health sciences : Pharmacy, pharmacology & toxicology
http://hdl.handle.net/2268/37927
A propos des transformations de la strychnine et (à propos des principes actifs) des Strychnos curarisants africains
French
[en] Instability of strychnine and active principles of Strychnos usambarensis
Angenot, Luc mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Bisset, Norman mailto [ > > ]
Denoël, Albert [ > > ]
Phillipson, J. mailto [ > > ]
1976
Journal de Pharmacie de Belgique
Nationale Pharmaceutique
31
5
509-510
Yes (verified by ORBi)
International
0047-2166
Bruxelles
Belgique
[en] strychnine ; pseudostrychnine ; genostrychnine ; chloromethostrychninium ; quaternary alkaloids ; Strychnos sp
[en] Strychnine is unstable under light in chloroformic solution and is partly transformed in pseudostrychnine, genostrychnine (Nb-oxy-strychnine) and chloromethostrychninium (a quaternary derivative). In other respects the curarizing activity of African Strychnos (e.g. Strychnos usambarensis) is not due to isostrychnine as erroneously written by TURKOVIC (J.Pharm Belg. 1976, 31, 277-286) but to quaternary alkaloids like C-dihydrotoxiferine, C-curarine, afrocurarine and C-calebassine (cf L.ANGENOT et al. Arch. Intern. Pharmacodyn. Ther. 1975, 215, 246-258).
http://hdl.handle.net/2268/37927

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