Référence : Antiinflammatory Prodelphinidins from Black Currant (Ribes nigrum) Leaves
Scientific journals : Short communication
Human health sciences : Pharmacy, pharmacology & toxicology
http://hdl.handle.net/2268/37306
Antiinflammatory Prodelphinidins from Black Currant (Ribes nigrum) Leaves
English
Tits, Monique[Université de Liège - ULg > Département de pharmacie > Phytochimie et phytothérapie >]
Angenot, Luc[Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Damas, Jacques[Université de Liège - ULg > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques >]
[en] Ribes nigrum ; Black Currant Leaves ; prodelphinidins ; anti-inflammatory activity ; carrageenann model
[en] In a study to select anti-inflammatory medicinal plants, we have observed that extracts of Ribes nigrum significantly inhibited at a dose of 50mg/kg i.p. the carrageenan rat paw edema. We have now proved that the most active fractions contained proanthocyanidins . In the present study, we report on the isolation of three bioactive compounds: two prodelphinidins dimers and a new trimeric one.