Article (Scientific journals)
The Epidemiology of Prolactinomas
Ciccarelli, A.; Daly, Adrian; Beckers, Albert
2005In Pituitary, 8 (1), p. 3-6
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Keywords :
prolactin; prolactinoma; pituitary; tumor; inherited; neoplasm; epidemiology
Abstract :
[en] Prolactin-secreting tumors (prolactinomas), the most frequently occurring pituitary tumor, have a frequency that varies with age and sex. They occur most frequently in females aged 20 to 50 years old, at which time the female-to-male ratio is approximately 10:1. In the pediatric-adolescent age group, prolactinomas have a prevalence of 100/million population, and account for less than 2% of all intracranial tumors. Prolactinomas occur in approximately 30% of patients with multiple endocrine neoplasia type 1 and in this setting, they may be more aggressive than their sporadic counterparts. Patients with Carney complex or McCune-Albright syndrome may exhibit hyperprolactinemia due to a pituitary tumor derived from somatomammotropic cells that secrete both growth hormone and prolactin. Few familial cases of prolactinoma unrelated to MEN-1 are reported in literature.
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
Ciccarelli, A.
Daly, Adrian  
Beckers, Albert ;  Université de Liège - ULiège > Département des sciences cliniques > Endocrinologie
Language :
English
Title :
The Epidemiology of Prolactinomas
Publication date :
January 2005
Journal title :
Pituitary
ISSN :
1386-341X
eISSN :
1573-7403
Publisher :
Springer, Netherlands
Volume :
8
Issue :
1
Pages :
3-6
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 19 May 2010

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