Reference : La régulation de l'expression des gènes du virus de la varicelle et du zona
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
Human health sciences : Immunology & infectious disease
http://hdl.handle.net/2268/37158
La régulation de l'expression des gènes du virus de la varicelle et du zona
French
Piette, Jacques mailto [Université de Liège - ULg > Département des sciences de la vie > Virologie - Immunologie >]
Defechereux, Patricia [> > > >]
Baudoux, Laurence [> > > >]
Melen-Lamalle, Laurence mailto [Université de Liège - ULg > Département des sciences cliniques > Labo de biologie des tumeurs et du développement >]
Debrus, S. [ > > ]
Sadzot-Delvaux, Catherine mailto [Université de Liège - ULg > Département des sciences de la vie > Virologie et immunologie > >]
Merville, Marie-Paule mailto [Université de Liège - ULg > Département de pharmacie > Chimie médicale >]
Rentier, Bernard mailto [Université de Liège - ULg > Département de Microbiologie > Virologie fondamentale et Immunologie > >]
1992
Annales de Médecine Vétérinaire
Annales Medecine Veterinaire
136
8
627-635
Yes (verified by ORBi)
International
0003-4118
Liège
Belgique
[en] Herpesvirus ; Regulatory proteins
[en] Varicella-zoster virus (VZV) belongs to the alphaherpesvirus family and shares many important structural and functional similarities with other members of the family such as herpes simplex virus type 1 (HSV-1). VZV is responsible for two different clinical syndromes, varicella which is the result of the primary infection and zoster which is due to virus reactivation remaining latent in the peripheral nervous system. VZV DNA is 124,884 base pair long and encodes four regulatory proteins (IE4, IE61, IE62 and IE63). Using transient expression systems, we have shown that IE4, IE62 and IE63 can regulate the expression of an indicator gene driven by various VZV promoter regions, demonstrating that these proteins play important roles in the infectious cycle.
Researchers
http://hdl.handle.net/2268/37158

There is no file associated with this reference.

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.