Reference : The bovine (Bos taurus) CD11a-encoding cDNA: molecular cloning, characterisation and ...
Scientific journals : Article
Life sciences : Genetics & genetic processes
http://hdl.handle.net/2268/35076
The bovine (Bos taurus) CD11a-encoding cDNA: molecular cloning, characterisation and comparison with the human and murine glycoproteins
English
Fett, Thomas mailto [Université de Liège - ULg > Département de Morphologie et Pathologie > Pathologie spéciale et autopsies > >]
Zecchinon, Laurent mailto [Université de Liège - ULg > Département de Morphologie et Pathologie > Pathologie spéciale et autopsies > >]
Baise, Etienne mailto [Université de Liège - ULg > Département des sciences de la vie > Macromolécules biologiques > >]
Desmecht, Daniel mailto [Université de Liège - ULg > Département de Morphologie et Pathologie > Pathologie spéciale et autopsies > >]
2004
Gene
Elsevier Science Bv
325
97-101
Yes (verified by ORBi)
International
0378-1119
Amsterdam
[en] integrins ; LFA-1 ; ICAM ; adhesion ; cattle
[en] The bovine cDNA encoding CD11 a cell-surface glycoprotein involved in multiple leukocyte functions, was sequenced and compared with the human and murine sequences. Despite some focal differences, it shares all the main characteristics of its known mammalian homologs. Along with the bovine CD18-encoding cDNA, which is available for a long time, the sequence data provided here will allow the successful expression of bovine CD11a, thus giving the first opportunity to express the Bos taurus beta(2)-integrin CD11a/CD18 (LFA-1, alpha(L)beta(2)) in vitro as a tool to examine the specificities of inflammation in the bovine species. (C) 2003 Elsevier B.V. All rights reserved.
Researchers ; Professionals
http://hdl.handle.net/2268/35076

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