Reference : Cloning and characterisation of the primary structure of the sheep lymphocyte function-a...
Scientific journals : Article
Human health sciences : Immunology & infectious disease
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/2268/35022
Cloning and characterisation of the primary structure of the sheep lymphocyte function-associated antigen-1 alpha subunit
English
Fett, Thomas mailto [Université de Liège - ULg > Département de Morphologie et Pathologie > Pathologie spéciale et autopsies > >]
Zecchinon, Laurent [Université de Liège - ULg > Département de Morphologie et Pathologie > Pathologie spéciale et autopsies > >]
Baise, Etienne mailto [Université de Liège - ULg > Département des sciences de la vie > Macromolécules biologiques >]
Desmecht, Daniel mailto [Université de Liège - ULg > Département de Morphologie et Pathologie > Pathologie spéciale et autopsies > >]
2005
Molecular Immunology
Pergamon-Elsevier Science Ltd
42
12
1503-1508
Yes (verified by ORBi)
International
0161-5890
Oxford
[en] integrin ; LFA-1 ; ICAM ; adhesion ; ovine
[en] The leukocyte integrins play a critical role in a number of cellular adhesive interactions during the immune response. The ovine cDNA encoding CD1 1a, the predominant a subunit of the beta(2)-integrin family, was sequenced and compared with the human, bovine and murine sequences. Despite some focal differences, it shares all the main characteristics of its known mammalian homologues. Along with the ovine CD18-encoding cDNA, which is available for a few months, the sequence data provided here will allow the Ovis aries beta(2)-integrin CD1 1a/CD18 (LEA-1, alpha(L)beta 2) expression in vitro as a tool to examine the specificities of inflammation in the ovine species. (c) 2005 Elsevier Ltd. All rights reserved.
Researchers ; Professionals
http://hdl.handle.net/2268/35022
10.1016/j.molimm.2005.01.005

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