Reference : Molecular characterization of the caprine (Capra hircus) lymphocyte function-associated ...
Scientific journals : Article
Life sciences : Veterinary medicine & animal health
http://hdl.handle.net/2268/35019
Molecular characterization of the caprine (Capra hircus) lymphocyte function-associated antigen-1 alpha subunit
English
Fett, Thomas mailto [Université de Liège - ULg > Département de morphologie et pathologie > Pathologie spéciale et autopsies >]
Zecchinon, Laurent [Université de Liège - ULg > Département de morphologie et pathologie > Pathologie spéciale et autopsies >]
Baise, Etienne mailto [Université de Liège - ULg > Département des sciences de la vie > Macromolécules biologiques >]
Desmecht, Daniel mailto [Université de Liège - ULg > Département de morphologie et pathologie > Pathologie spéciale et autopsies >]
2005
BMC Veterinary Research
BioMed Central
1:4
Yes (verified by ORBi)
International
1746-6148
[en] caprine ; lymphocyte
[en] Background: Lymphocyte function-associated antigen-1 (LFA-1, CD11a/CD18, alpha L beta 2) is
required for many cellular adhesive interactions during the immune response.
Results: The Capra hircus CD11a-encoding cDNA was sequenced and compared with its human,
murine, rat, bovine and ovine counterparts. Despite some focal differences, it shares all the main
characteristics of its known mammalian homologues.
Conclusion: Therefore, along with the caprine CD18-encoding cDNA, which has been available
for a few months, the sequence data revealed here will allow the Capra hircus LFA-1 expression in vitro as a tool to explore the specificities of inflammation in the caprine species.
Service public fédéral Santé publique, Sécurité de la Chaîne alimentaire et Environnement
Researchers ; Professionals
http://hdl.handle.net/2268/35019

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