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Acute ethanol increases taurine but neither glutamate nor GABA in the nucleus accumbens of male rats: a microdialysis study.
Dahchour, Abdelkhader; Quertemont, Etienne; De Witte, Philippe
1994In Alcohol and Alcoholism, 29 (5), p. 485-7
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Keywords :
Alcoholic Intoxication; Animals; Chromatography; Ethanol; Glutamic Acid; Injections; Male; Microdialysis; Nucleus Accumbens; Rats; Taurine; gamma-Aminobutyric Acid
Abstract :
[en] The effects of acute intraperitoneal administration of ethanol (1-3 g/kg body wt) on the extracellular concentrations of glutamate (GLU), taurine (TAU) and gamma-aminobutyric acid (GABA) in rat brain nucleus accumbens were studied by the microdialysis technique coupled to HPLC-EC detection. Levels of GLU and GABA were not affected by ethanol, whereas those of TAU were increased by doses of the drug of 2-3 g/kg.
Research center :
Centre de Neurosciences Cognitives et Comportementales - ULiège
Disciplines :
Pharmacy, pharmacology & toxicology
Neurosciences & behavior
Author, co-author :
Dahchour, Abdelkhader;  Université Catholique de Louvain - UCL
Quertemont, Etienne  ;  Université de Liège - ULiège > Département des sciences cognitives > Psychologie quantitative
De Witte, Philippe;  Université Catholique de Louvain - UCL
Language :
English
Title :
Acute ethanol increases taurine but neither glutamate nor GABA in the nucleus accumbens of male rats: a microdialysis study.
Publication date :
1994
Journal title :
Alcohol and Alcoholism
ISSN :
0735-0414
eISSN :
1464-3502
Publisher :
Oxford University Press, Oxford, United Kingdom
Volume :
29
Issue :
5
Pages :
485-7
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 11 May 2010

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