[en] The activity of diploceline is relatively weak as compared to metronidazole on Entamoeba histolytica and Trichomonas vaginalis. The quaternary alkaloid does not produce any inhibition of Plasmodium falciparum growth at 25 micrograms/ml (maximum tested concentration).
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Gasquet, Monique
Quetin-Leclercq, Joëlle
Timon-David, Pierre
Balansard, Guy
Angenot, Luc ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Language :
English
Title :
Antiparasitic Properties of Diploceline, a Quaternary Alkaloid from Strychnos gossweileri
Publication date :
1992
Journal title :
Planta Medica
ISSN :
0032-0943
eISSN :
1439-0221
Publisher :
Georg Thieme Verlag Stuttgart, New York, United States - New York