Reference : Cytotoxic Activity of Some Triterpenoid Saponins
Scientific journals : Letter to the editor
Human health sciences : Pharmacy, pharmacology & toxicology
Cytotoxic Activity of Some Triterpenoid Saponins
Quetin-Leclercq, J. [ > > ]
Elias, R. [ > > ]
Balansard, G. [ > > ]
Bassleer, R. [ > > ]
Angenot, Luc mailto [Université de Liège - ULg > Département de pharmacie > Pharmacognosie >]
Planta Medica
Georg Thieme Verlag Stuttgart
Yes (verified by ORBi)
New York
[en] Saponins ; Cytotoxic Activity ; Hedera helix ; Calendula arvensis ; Calendula officinalis ; Sapindus mukurossi
[en] The present note deals with the cytotoxic activity of purified saponins of hedera helix and of saponins isolated from other plants ( Calendula officinalis, C. arvensis and Sapindus mukurossi with a view to the detection of possible structure-activity relationships. The most active compounds are the monodesmosides which show some degree of cytotoxicity at concentrations of 10 micrograms/ml and above. Among them, alpha- and beta-hederin are the most potent substances.

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Planta Med. 58 _ 1992 pp 279 _281.pdfPublisher postprint150.64 kBRequest copy

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