Reference : Les cellules ECL et leurs récepteurs: rôle physiologique et intérêt physiopathologique
Scientific journals : Article
Human health sciences : Gastroenterology & hepatology
http://hdl.handle.net/2268/33622
Les cellules ECL et leurs récepteurs: rôle physiologique et intérêt physiopathologique
French
[en] Enterochromaffin-Like Cells and Their Receptors: Physiological Role and Physiopathological Significance
Belaiche, Jacques mailto [Université de Liège - ULg > Département des sciences cliniques > Hépato-gastroentérologie]
Delwaide, Jean mailto [Université de Liège - ULg > > Gastro-Entérologie-Hépatologie >]
Louis, Edouard mailto [Université de Liège - ULg > Département des sciences cliniques > Hépato-gastroentérologie >]
Gast, Pierrette mailto [Centre Hospitalier Universitaire de Liège - CHU > > Gastro-Entérologie-Hépatologie >]
1993
Acta Gastro-Enterologica Belgica
56
3-4, May-Aug
235-44
Yes (verified by ORBi)
International
0001-5644
[en] The enterochromaffin-like (ECL) cells represent the predominating endocrine cell population in the oxyntic mucosa of the stomach. They are under the influence of gastrin. Recently, a histamine production was shown within the secretory granules of ECL cells. ECL cells appear to play a crucial role in the physiology of gastric acid secretion. There are many unknowns concerning the intervention of other trophic factors in addition to gastrin and concerning the receptors located on the cells. ECL cell hyperplasia is a well documented consequence of hypergastrinemia. The latter can result from a gastrinoma or from a reduction of gastric acid secretion related to pernicious anemia or to long-term treatment with antisecretory drugs.
http://hdl.handle.net/2268/33622

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