Article (Scientific journals)
Evaluation of the GERD Impact Scale, an international, validated patient questionnaire, in daily practice. Results of the ALEGRIA study.
Louis, Edouard; Tack, Jacques; Vandenhoven, G. et al.
2009In Acta Gastro-Enterologica Belgica, 72 (1), p. 3-8
Peer Reviewed verified by ORBi
 

Files


Full Text
Evaluation of the GERD Impact Scale... 2009-Acta Gastroenterol Belg.pdf
Publisher postprint (119.76 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Activities of Daily Living; Adult; Aged; Belgium/epidemiology; Female; Gastroesophageal Reflux/drug therapy/epidemiology/physiopathology; Health Status; Humans; Life Style; Male; Middle Aged; Physician's Practice Patterns/statistics & numerical data; Physicians; Proton Pump Inhibitors/therapeutic use; Questionnaires/standards; Severity of Illness Index
Abstract :
[en] BACKGROUND AND STUDY AIMS: Gastroesophageal reflux disease (GERD) is a common chronic disease that is primarily diagnosed based on symptom severity and frequency. This study gathered epidemiological data in a population of GERD patients and evaluated the added-value of the GERD Impact Scale (GIS), a novel, validated patient questionnaire, as a tool for initial and long-term patient management. PATIENTS AND METHODS: This observational study recruited patients (296 study centers) with symptomatic GERD and a history of erosive, or reflux, esophagitis. Symptoms were assessed by GIS and physician-subject interview and recorded at baseline (visit 1), at 4-6 weeks (visit 2) and 8-14 weeks (visit 3); also recorded at each visit was the physician's assessment of GERD severity and treatment changes. Analyses were performed on an intent-to-treat basis. RESULTS: Subjects (n = 1919; mean age, 55 years) were 54% female. Lifestyle characteristics included stress (approximately 70% of subjects), mean daily consumption of five cups of caffeine-containing beverages (approximately 70%), alcohol consumption of approximately nine units per week (approximately 50%) and smoking/ex-smoker (41%). Proton pump inhibitors were prescribed in 99% of cases: mainly esomeprazole (82%), with a median dose of 40 mg. Prescribed therapy was changed (mainly dosage levels) between visits in approximately 60% of subjects. The severity of GERD symptoms and GIS scores decreased substantially throughout the study. Mean GIS scores correlated positively with increasing GERD severity and clinical judgment at all visits. Physicians reported that the GIS helped them define the appropriate treatment for the patient and to evaluate the patient's response to treatment in 81% of cases. CONCLUSIONS: This study demonstrates the added-value and usefulness of the patient self-assessment GIS as a management tool for GERD.
Disciplines :
Gastroenterology & hepatology
Author, co-author :
Louis, Edouard  ;  Université de Liège - ULiège > Département des sciences cliniques > Hépato-gastroentérologie - Relations académiques et scientifiques (Médecine)
Tack, Jacques ;  Université de Liège - ULiège > Département ArGEnCo > Département ArGEnCo
Vandenhoven, G.
Taeter, C.
Language :
English
Title :
Evaluation of the GERD Impact Scale, an international, validated patient questionnaire, in daily practice. Results of the ALEGRIA study.
Publication date :
2009
Journal title :
Acta Gastro-Enterologica Belgica
ISSN :
0001-5644
eISSN :
1784-3227
Publisher :
Acta Medica Belgica, Bruxelles, Belgium
Volume :
72
Issue :
1
Pages :
3-8
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 21 February 2010

Statistics


Number of views
115 (1 by ULiège)
Number of downloads
3 (0 by ULiège)

Scopus citations®
 
12
Scopus citations®
without self-citations
12

Bibliography


Similar publications



Contact ORBi