Reference : Liver transplantation from donation after cardiac death donors: initial Belgian exper...
Scientific journals : Article
Human health sciences : Surgery
Human health sciences : Gastroenterology & hepatology
http://hdl.handle.net/2268/33336
Liver transplantation from donation after cardiac death donors: initial Belgian experience 2003-2007.
English
Detry, Olivier mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
Donckier, Vincent [> > > >]
Lucidi, Valerio [> > > >]
Ysebaert, Dirk [> > > >]
Chapelle, Thierry [> > > >]
Lerut, Jan [> > > >]
Ciccarelli, Olga [> > > >]
Pirenne, Jacques [> > > >]
Monbaliu, Diethaard [> > > >]
De Roover, Arnaud mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
Honore, Pierre mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
Rogiers, Xavier [> > > >]
De Hemptinne, Bernard [> > > >]
Troisi, Roberto [> > > >]
Jun-2010
Transplant International
23
6
611-618
Yes (verified by ORBi)
International
0934-0874
1432-2277
[en] extended donor criteria ; graft failure ; graft outcome ; non-heart beating donation ; ischemic bile duct lesion
[en] The Belgian experience with donation after cardiac death (DCD) liver transplantation (LT) was retrospectively reviewed, particularly evaluating patient and graft survivals, and biliary complications. From 2003 to 2007, 58 DCD-LT were performed in Belgium. Mean procurement total warm ischemia time was 25 +/- 2 min (mean +/- SEM). Mean cold ischemia time was 451 +/- 18 min. Mean follow-up was 23 +/- 2.2 months. Post-transplant peak aspartate aminotransminases was 2241 +/- 338 UI/l. Patient survivals at 1 month, 1 and 3 years, were 91.3%, 83.3% and 66.9% respectively. Graft survivals at 1 month, 1 and 3 years, were 84.4%, 72.4% and 48.8% respectively. Two patients (3.4%) developed primary nonfunction. Regarding the biliary complications, seven grafts (12%) were lost because of intrahepatic cholangiopathy, and 12 other patients (20.6%) developed bile duct stenoses requiring endoscopic and/or surgical management. The rate of symptomatic ischemic biliary lesions for grafts surviving more than 3 months was 38% (19/50). Although DCD organ donors may be a source of viable liver grafts, results were inferior to those obtained with donation after brain death LT in this series. Prognostic criteria have to be developed to improve results of DCD-LT.
Professionals ; Students ; General public
http://hdl.handle.net/2268/33336
10.1111/j.1432-2277.2009.01029.x

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