Reference : Baseline brain activity fluctuations predict somatosensory perception in humans
Scientific journals : Article
Human health sciences : Neurology
http://hdl.handle.net/2268/33048
Baseline brain activity fluctuations predict somatosensory perception in humans
English
Boly, Mélanie mailto [Université de Liège - ULg > Centre de Recherches du Cyclotron - Comagroup > Neurologie > > >]
Balteau, Evelyne [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Schnakers, Caroline mailto [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Degueldre, Christian [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Moonen, Gustave [Université de Liège - ULg > Département des sciences cliniques > Neurologie - Doyen de la Faculté de Médecine]
Luxen, André [Université de Liège - ULg > Département de chimie (sciences) > Chimie organique de synthèse - Centre de recherches du cyclotron >]
Phillips, Christophe [Université de Liège - ULg > > Centre de recherches du cyclotron >]
Peigneux, Philippe mailto [Université de Liège - ULg > > Centre de recherches du cyclotron]
Maquet, Pierre mailto [Université de Liège - ULg > > Centre de recherches du cyclotron]
Laureys, Steven mailto [Université de Liège - ULg > > Centre de recherches du cyclotron]
17-Jul-2007
Proceedings of the National Academy of Sciences of the United States of America
Natl Acad Sciences
104
29
12187-12192
Yes (verified by ORBi)
International
0027-8424
Washington
[en] consciousness ; functional MRI ; pain
[en] In perceptual experiments, within-individual fluctuations in perception are observed across multiple presentations of the same stimuli, a phenomenon that remains only partially understood. Here, by means of thulium-yttrium/aluminum- garnet laser and event-related functional MRI, we tested whether variability in perception of identical stimuli relates to differences in prestimulus, baseline brain activity. Results indicate a positive relationship between conscious perception of low-intensity somatosensory stimuli and immediately preceding levels of baseline activity in medial thalamus and the lateral frontoparietal network, respectively, which are thought to relate to vigilance and "external monitoring." Conversely, there was a negative correlation between subsequent reporting of conscious perception and baseline activity in a set of regions encompassing posterior cingulate/ precuneus and temporoparietal cortices, possibly relating to introspection and self-oriented processes. At nociceptive levels of stimulation, pain-intensity ratings positively correlated with baseline fluctuations in anterior cingulate cortex in an area known to be involved in the affective dimension of pain. These results suggest that baseline brain-activity fluctuations may profoundly modify our conscious perception of the external world.
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS ; Fondation Médicale Reine Elisabeth ; Mind Science Foundation
http://hdl.handle.net/2268/33048
10.1073/pnas.0611404104

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