ORBi: Rosu Frédéric - Telomestatin-induced stabilization of the human telomeric DNA quadruplex monitored by electrospray mass spectrometry

Reference : Telomestatin-induced stabilization of the human telomeric DNA quadruplex monitored by el...


	Document type :	Scientific journals : Short communication
	Discipline(s) :	Physical, chemical, mathematical & earth Sciences : Chemistry Life sciences : Biochemistry, biophysics & molecular biology
	To cite this reference:	http://hdl.handle.net/2268/329

Title :	Telomestatin-induced stabilization of the human telomeric DNA quadruplex monitored by electrospray mass spectrometry
Language :	English
Author, co-author :	Rosu, Frédéric [Université de Liège - ULg > > Chimie physique, spectrométrie de masse >]
	Gabelica, Valérie [Université de Liège - ULg > > Chimie physique, spectrométrie de masse >]
	Shin-ya, Kazuo [> > > >]
	De Pauw, Edwin [Université de Liège - ULg > > Chimie physique, spectrométrie de masse >]
Publication date :	2003
Journal title :	Chemical Communications
Publisher :	Royal Society of Chemistry
Issue/season :	21
Pages :	2702-2703
Audience :	International
ISSN :	1359-7345
e-ISSN :	1364-548X
City :	Cambridge
Country :	United Kingdom
Keywords :	[en] mass spectrometry ; DNA ; telomestatin ; quadruplex ; duplex ; kinetics
Abstract :	[en] Electrospray mass spectrometry (ESI-MS) was used to monitor the kinetics of duplex formation between the human telomeric DNA quadruplex and its complementary strand; the complexation of telomestatin to the G-quadruplex delays the unwinding of the quadruplex structure and formation of the duplex.
Research units :	Centre Interfacultaire d'Analyse des Résidus en Traces - CART
Funders :	Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Target :	Researchers
Permalink :	http://hdl.handle.net/2268/329
DOI :	10.1039/b309394h

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	File	Commentary	Version	Size	Access
Restricted access	2003_ChemComm_telomestatin.pdf	No commentary	Publisher postprint	119.32 kB	Request copy
Restricted access	2003 Chemcomm_final draft.pdf	No commentary	Author postprint	222.07 kB	Request copy

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